Response Variability to Psychotropic DrugsW. Janke |
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Page 243
... treatment , i.e. , symptoms or groups of symptoms under treatment ( or groups of patients characterized by groups of symptoms associated with the disorder ) characteristics that are not the object of treatment , pre- sumably do not ...
... treatment , i.e. , symptoms or groups of symptoms under treatment ( or groups of patients characterized by groups of symptoms associated with the disorder ) characteristics that are not the object of treatment , pre- sumably do not ...
Page 247
... treatment . In 1974 , Beckman and Goodwin used 16 unipolar depressed patients to compare the response to imipramine ... treatment level of MHPG was relatively high responsed better to ami- triptyline treatment than those for whom ...
... treatment . In 1974 , Beckman and Goodwin used 16 unipolar depressed patients to compare the response to imipramine ... treatment level of MHPG was relatively high responsed better to ami- triptyline treatment than those for whom ...
Page 253
... treatment ( e.g. iproniazid ) versus no treatment ( i.e. placebo ) as forming a dichotomized variable in a composite sample which com- prises both placebo - treated and iproniazid - treated patients . Biserial correlation coefficients ...
... treatment ( e.g. iproniazid ) versus no treatment ( i.e. placebo ) as forming a dichotomized variable in a composite sample which com- prises both placebo - treated and iproniazid - treated patients . Biserial correlation coefficients ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn