Response Variability to Psychotropic DrugsW. Janke |
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Page 79
... Females 4.1.1 Gross organismic response . A larger group of results demonstrates higher reactivity in females as for instance those from clinical studies on schizophrenic patients reporting significantly better improvement with ...
... Females 4.1.1 Gross organismic response . A larger group of results demonstrates higher reactivity in females as for instance those from clinical studies on schizophrenic patients reporting significantly better improvement with ...
Page 80
... females which can be due to a ) genetic sex linked factors b ) interactions of the drugs with female sex hormones c ... females , 3. by more sensitive cognitive perception of drug induced physical changes as aversive stimuli in females ...
... females which can be due to a ) genetic sex linked factors b ) interactions of the drugs with female sex hormones c ... females , 3. by more sensitive cognitive perception of drug induced physical changes as aversive stimuli in females ...
Page 81
W. Janke. plasma of females who do not use sex hormones ( Routledge and others , 1981 ) . Finally , the greater variability in time to reach peak concentrations of chlordiazepoxide observed by Greenblatt ( 1974 ) in females may be taken ...
W. Janke. plasma of females who do not use sex hormones ( Routledge and others , 1981 ) . Finally , the greater variability in time to reach peak concentrations of chlordiazepoxide observed by Greenblatt ( 1974 ) in females may be taken ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn