Response Variability to Psychotropic DrugsW. Janke |
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Page 35
... ENVIRONMENTAL AND SITUATIONAL FACTORS One of the most embarrassing problems in psychopharmacology results from the fact that psychotropic drugs have varying effects according to the environmental conditions and situations in which they ...
... ENVIRONMENTAL AND SITUATIONAL FACTORS One of the most embarrassing problems in psychopharmacology results from the fact that psychotropic drugs have varying effects according to the environmental conditions and situations in which they ...
Page 37
... environmental and situational factors more clearly . The main questions which should be investigated in further experiments are the following : ( 1 ) By which mechanisms is the influence of environmental and situa- tional factors ...
... environmental and situational factors more clearly . The main questions which should be investigated in further experiments are the following : ( 1 ) By which mechanisms is the influence of environmental and situa- tional factors ...
Page 58
... environmental and situational factors them- selves . Compared to traits , environmental and situational factors as predictors of drug response have the advantage that they refer to the present state . The problem , however , is that ...
... environmental and situational factors them- selves . Compared to traits , environmental and situational factors as predictors of drug response have the advantage that they refer to the present state . The problem , however , is that ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn