Response Variability to Psychotropic DrugsW. Janke |
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Page 108
... drugs ? A recent report on hypnotic sus- ceptability to various depressant drugs in rats selectively bred for differential sensitivity to ethyl alcohol suggests that there may not be a simple answer to those questions ( Riley and others ...
... drugs ? A recent report on hypnotic sus- ceptability to various depressant drugs in rats selectively bred for differential sensitivity to ethyl alcohol suggests that there may not be a simple answer to those questions ( Riley and others ...
Page 129
... drugs which seem to push a given person in one direction or other . Thus stimulant and depressant drugs would appear to have introverting and extraverting effects ; dexamphetamine sulfate might be an example of the former , and ...
... drugs which seem to push a given person in one direction or other . Thus stimulant and depressant drugs would appear to have introverting and extraverting effects ; dexamphetamine sulfate might be an example of the former , and ...
Page 130
... depressant drug administration . Our prediction would be that the stimulant drug would displace the subject's performance on a given test known to correlate with E in the direction of E- , i.e. greater introversion , while the depressant ...
... depressant drug administration . Our prediction would be that the stimulant drug would displace the subject's performance on a given test known to correlate with E in the direction of E- , i.e. greater introversion , while the depressant ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn