Response Variability to Psychotropic DrugsW. Janke |
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Page 24
... correlations between blood concentrations of neuroleptics or antide- pressants and clinical response by Modestin and Petrin ( 1976 ) and by Glassman and Perel ( 1978 ) yielded the following results ( Table 3 ) : TABLE 3 Results of ...
... correlations between blood concentrations of neuroleptics or antide- pressants and clinical response by Modestin and Petrin ( 1976 ) and by Glassman and Perel ( 1978 ) yielded the following results ( Table 3 ) : TABLE 3 Results of ...
Page 213
... correlation . Additionally a correction for shrinking was performed to make multiple correlations based on different numbers of predictors comparable . As Table 2 shows the best multiple predictions of drug effects could be performed in ...
... correlation . Additionally a correction for shrinking was performed to make multiple correlations based on different numbers of predictors comparable . As Table 2 shows the best multiple predictions of drug effects could be performed in ...
Page 253
... correlations ; a negative correlation implies that , relative to placebo , the active treatment is associated with a diminution of the symptom . AVPD -1 ° As could be anticipated from Tables 1 , 2 , Personality and Pharmacotherapeutic ...
... correlations ; a negative correlation implies that , relative to placebo , the active treatment is associated with a diminution of the symptom . AVPD -1 ° As could be anticipated from Tables 1 , 2 , Personality and Pharmacotherapeutic ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn