Response Variability to Psychotropic DrugsW. Janke |
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Page 107
... activity of the en- zyme , cholinesterase , in the rat cerebral cortex has been reported ( Roderick , 1960 ) . Large phenotypic differences between inbred strains of mice in cholinesterase activity has also been noted ( Pryor and others ...
... activity of the en- zyme , cholinesterase , in the rat cerebral cortex has been reported ( Roderick , 1960 ) . Large phenotypic differences between inbred strains of mice in cholinesterase activity has also been noted ( Pryor and others ...
Page 118
... activity in enzymes involved in neurotransmission and performed tasks more readily than animals living in isolation ( Rosenzweig and others , 1960 ) . That the task or situation in which individuals are engaged may affect responses to ...
... activity in enzymes involved in neurotransmission and performed tasks more readily than animals living in isolation ( Rosenzweig and others , 1960 ) . That the task or situation in which individuals are engaged may affect responses to ...
Page 215
... activity due to promethazine action . Relatively narrow traits such as phobic tendencies , mental activity , deactivation , and sensation seeking are mainly used in the prediction of drug action on subjective activity , although anxiety ...
... activity due to promethazine action . Relatively narrow traits such as phobic tendencies , mental activity , deactivation , and sensation seeking are mainly used in the prediction of drug action on subjective activity , although anxiety ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn