Mesmedee Hassan Jelowdar had complained for some days of rheumatism of the knee and shoulder ; was treated with colchicum and Dover's powder, without benefit; had then pain in the region of the heart, shoulder-blade and left arm; action of the heart much excited. Pulse about 90. Could detect no peculiar sounds in the heart, but as a measure of precaution against pericarditis, he was bled and put upon calomel and opium.

26th January, the pain in the region of the heart, the scapula and arm, and in the knee, is more severe; his pulse is not like that of pericarditis, nor are the other symptoms-no fever-complains also of sleeping and insensibility of one side at a certain hour of the night.

27th. To omit the pills and to take calomel gr. v at night. Pulv. jalap co. in the morning.

28th.-Has not been freely purged. Complains of increased pain in the left breast and shoulder, and the numbness of the hands and feet more constant and annoying. Countenance anxious. To take ferri carb. gr. x scammonii gr. v statim et ferri carb. j vespere.

29th.-Bowels freely opened and the numbness ceased-no return of that at night, but still pain in the breast, and excited action of heart considerable. After a few more doses of iron this gradually subsided, as well as the pains in the knee and shoulder.

Saduck Khan, æt. about 28, a very powerful man, a wrestler, subject of late to attacks of ague, quartan, tertian, and quotidian, on which quinine has had

little or no effect. Has complained of the leg and arm going to sleep for several successive nights, and has spasms of the thumbs. To take calomel gr. v for

three successive nights.

27th January.-Mouth touched by mercury-ague gone, and numbness of the leg and arm has ceased.

28th.-Has again had numbness of the arm and leg. To take two scruple doses of carbonate of iron. After this he had no return of his symptoms.

29th January. A woman about the age of thirty, who had some days ago taken viij of castor oil, instead of as many drachms, was weakened by purging, but was regaining her strength. Is said to-day to have had three successive fits of fainting. She has pain and numbness of both arms, like paralysis, but has no tingling sensation. Pulse rather weak. Ordered ferri carb. j stat. et repetatur vespere. If she has a return of the fit, to have an enema of zij of assafoetida. Had no return of the fit, and the numbness ceased soon after the first dose of iron.

Kutchuk Khan, nicknamed the little, from his enormous size and corpulency, having fallen into a fit, with convulsions and insensibility, his people became alarmed, and sent to me for medicine, and at the same time to the chief physician, or Hakim Bashee, to come quickly, as he was dying. Being from home, my apothecary gave them a dose of iron, which was administered immediately. In about an hour, when the Hakim Bashee arrived, and found his patient conversing merrily with his friends, he was excessively indignant at having been sent for on a

fool's errand; for they having with sufficient accuracy described a severe attack of apoplexy, while he found the man in apparently perfect health, nothing could persuade him that they were not what is called here, laughing at his beard.

M. Ta French cavalry officer, of florid complexion, having, about the time when this complaint first made its appearance, what were thought to be threatenings of apoplexy, was bled by the advice of the medical officer to the Russian mission. After this, he had a very severe fit, remaining many hours insensible; his servants continued assiduous in rubbing him, and he came to himself. He was again bled. Every night he had sensations of numbness of the leg and arm of one side, and twice again had fits, but less severe. He had suffered thus for 8 or 10 days, when he consulted me: I gave him two scruple doses of carbonate of iron; the first with 6 grains of scammony to be taken at noon, the other in the evening. That night he had no return of the numbness, nor did he experience it afterwards.

A few other cases of fits occurred, but having now lost their interest, I preserved no notes of them. A great number of people however, I may say almost the mass of the population in this immediate vicinity, were affected for some nights with sleeping of the leg or arm of one side. I experienced it myself, and found the sensation and the unnatural excitement of the heart extremely unpleasant; but it ceased after taking a dose of iron.

I found on inquiry, that at this time the complaint was confined to a narrow line of this and the neighbouring district. For some days, I saw and heard no more of it, till perhaps a week afterwards, when I was at the furthest extremity of the town visiting an hysterical patient who had symptoms of the same disorder. I was called to see Mirza Saleh, who had been discovered lying in his own room, insensible. When I arrived, he was beginning slowly to recover his senses, and could be roused a little but as he continued drowsy and stupid, I ordered him an enema of zii of assafoetida, and left him for a while. As no one had seen him at the commencement of the attack, I could not learn whether he had been seized with spasms or not. On my return two hours afterwards, I found him talking of his grievances in English with the Hakim Mirza Baba, in a very excited manner. I recommended him to take two doses of iron, and he had no return of his symptoms.

It was not till the 25th of February, and in another distant quarter of the town, that I saw another case of this complaint. On the evening of that day, on coming home, I found a note from Dr. Kapherr of the Russian mission, begging me to come without delay to see M. B a French

officer, commandant of a detachment in the service of the Shah. The commandant is a man of very quiet habits, aged about forty-five. Head rather large and neck short. I found him on my arrival

in a state of insensibility, the mouth drawn to the left side, and that side of the body paralytic. He had been in this state about six hours, but little account of his state previous to the attack could be collected from his servants. The pulse was rapidly sinking and nervous-now quick and irritable, now soft, weak and scarcely perceptible. A few teaspoonsfuls of æther. sulph. co. were given, and some 5 or 6 ounces of blood drawn from the arm, after which the pulse became steady. He now had an enema of zij of assafœtida, which was retained-and he continued in the same insensible paralytic state till 2 a.m., having been comatose for about fifteen hours. He then awoke as from a sleep, and walked to stool. In the morning I found him perfectly sensible, and nothing remaining of the paralysis but a sense of weariness in the limbs. He then took ol. ricini gifs, and had no return of his complaint. According to his own account, early in the morning he had been seized with the most urgent desire to make water, but found himself unable to do sohe continued to make frequent attempts in vain, and the agony of the urgency he describes as insufferable, until he lost his consciousness (apparently about 11 a.m.). When the injection operated, the water came without difficulty. He had no subsequent headache, nor any premonitory symptoms, such as sleeping of the hands or feet.

At another time, I should have considered this an attack of apoplexy, which from his appearance