Reactive Oxygen Species in Chemistry, Biology, and Medicine
Springer Science & Business Media, Jun 29, 2013 - Science - 232 pages
A NATO Advanced Study Institute on "Oxygen Radicals in Biological Systems: Recent Progress and New Methods of Study" was held in Braga, Portugal between Sep tember 1 and September 14, 1985, in order to consider the basic chemistry and biochem istry of activated oxygen (both radical and non-radical species) and their effect in biolog ical systems. This book summarizes the main lectures given at this meeting. While there is no attempt to cover all the major topics in the expanding subject of oxidative mechanisms in biology, an effort has been made to provide overviews on some key aspects of this field. The authors have attempted to convey a clear picture of both what is known and what remains unclear in their respective subjects. Not only are some of the techniques used for detecting activated oxygen species described, but also their strengths and limi tations. The chemistry of many of these species is discussed and the biological and/or pathological implications are carefully reviewed. The medical and therapeutic aspects of some of the well established pathways of damage and protection are analyzed. It is our hope that the material included in this book might be useful for both researchers and teachers at the graduate level. The success of this meeting was to a large extent due to the tireless committment of Professor Alberto Amaral and Dr. Concei~a:o Rangel; without their outstanding efforts in dealing with all the aspects of the organization, this summer school would not have been possible.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Glutathione Peroxidase Selenium and Vitamin E in Defense Against Reactive
Formation and Properties of Oxygen Radicals
The Autooxidation of Polyunsaturated Lipids
Organic Peroxy Free Radicals and the Role of Superoxide Dismutase
Determination of Dissolved Oxygen in Photosynthetic Systems and Protective
The SuperoxideGenerating NADPH Oxidase of White Blood Cells
Role of Reactive Oxygen Species and Lipid Peroxidation in ChemicallyInduced
Oxidative Effects of Physical Exercise
Oxidative and Peroxidative Damage and its Role in the Aging Process
Other editions - View all
Academic Press agents animals anion antioxidants arachidonic assay atom abstraction autoxidation Biochem Biol biological systems Biophys blood Cadenas calcium carbonyl catalase cells cellular Chem chemical chemiluminescence Chemistry Cilento complex components compounds concentration cyanobacteria cytochrome detection drug effect emission energy enzymatic enzyme erythrocytes exercise fatty acids Figure formation formed free radical glutathione peroxidase glutathione peroxidase activity GSSG human hydrogen atom hydroperoxide increased Ingold inhibition interaction intermediates intracellular levels linoleate lipid peroxidation liver low-level chemiluminescence magnetic mechanism menadione metabolism metabolites microsomal mitoxantrone molecular oxygen molecules NADPH oxidase neutrophils organic oxidative damage oxygen radicals peroxy radical peroxyl phagocytes Photobiol Photochem protein pulse radiolysis quenching quinones rate constants rats react reaction reactive oxygen species redox cycling reduced reductase resonance result role selenium shown singlet oxygen skeletal muscle Slater spin studies substrate Table thiol tion tissue toxic triplet carbonyls vitamin vitamin E vivo