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About 1 1 36 a major fire destroyed many of the city's wooden houses and St.
Paul's itself. In the rebuilding, houses of stone and tile began to appear, and
streets were paved and at least partially cleansed by open sewers and conduits.
By the ...
In 1796 Jenner began inoculations with material from cowpox (the bovine form of
the disease); and when he later inoculated the same Smallpox subject with
smallpox, the disease did not appear. This vaccination procedure — vaccination
But beginning in the 1930s these methods began to be supplemented by
physical approaches using drugs, electroconvulsive therapy, and surgery. The
first successful physical treatment in psychiatry was the induction of malaria in
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