able symptoms. Immediately after the application the patient is quieter, fresher, the fever ceases, the feeling of weakness leaves him. The applications are continued after all symptoms have disappeared. Burghardt has not met with a single failure. Of thirty-three cases, some of which were very dangerous, not one terminated fatally. Time of cure, two weeks.-Wiener Med. Wochenschrift, J. A. M. Asso.

DIURETIC ACTION OF SALICYLIC ACID.-Dr. Huber (Gaz. Hebd de Med., M. Rec., September 21), in twenty-five cases of rheumatism, noted augmentation of the urinary secretion after administration of the acid. He found the quantity of urine to increase in the twenty-four hours from sixteen to twenty-three ounces. Similar results were noted in cases of pleurisy. The diuretic dose of salicylic acid was about ten grains every three hours, until forty-five grains per day were administered. The diuresis augments from the first day, and continues on the following days. Huber would not advise the employment of this remedy in typhoid fever, and still less in the course of nephritis; in fact, he would restrict its use to cases of simple pleuritic effusion.

"Here I have

"Lame! lame!" sighed Mrs. Partington. been sufferin' the bigamies of death for three mortal weeks. First I was seized with the bleeding phrenology in the hampshire of the brain, which was exceeded by the stoppage of the left ventilator of the heart. This gave me inflammation of the left borax, and now I am sick with the chloroform morbus. There is no blessin' like that of health, particularly when you're ill."

MALIGNANT PUSTULE AND IODOFORM.-Dr. E. Rinonapoli, Bolletino della R. Accad. Med.-Ch. di. Napoli, Lancet, September 21, the method employed is that of several injections into and around the seat of the pustule of a ten per cent. solution of iodoform in ether. The pain attending the injec tions is of a severe burning character, but soon passes off. The beneficial effects are rapid in their appearance, In three or four hours after the injections, even in advanced cases, the fever lessens, the swelling around the pustule disappears, the tongue becomes clean, and the patient is able to sleep and to take food. The treatment appears to be of distinctly specific character, and to arrest at once the growth and mul

tiplication of the charbon bacillus. If applied at the outset of the attack, the effect is said to be almost magical.

PHTHISIS AND CARBONIC ACID. -Dr. Hugo Weber, Berlin kiin. Woch., Med. Rec., September 21. The method consists in administering to the patient a teaspoonful of bicarbo nate of soda before meals and following it with a glass of water containing twelve drops of muriatic acid. There is generated about half a pint (270 cc.) of carbonic acid gas, which is gradually absorbed and inhaled by the lungs. Weber reports nine cases favorably affected by this treatment. PHTHISIS AND WOOLEN CLOTHING.-Dr. Grechko has examined the effects of supplying phthisical patients with woolen clothing. He finds St. Petersburg Dissertations, Lancet, August 24) that the loss by the lungs and skin is greatly increased during the first twenty-four hours; the temperatur of the skin distinctly increased during the first day, but after that it begins to fail slowly, so that by the end of the week it has become normal.

"Uncle Pomp," said Colo el M. to a former slave, I hear that some of your darkies down on the lower place are afflicted with the itch."

"Bein' as it's you, boss," replied old Pompey, hesitatingly, "I mus' confess dat de Lawd has seen fit to afflick us dat way, for a fac."

Oh, doing anything for it?"

"Yes, sah; oh, yes, sah."

"What?"

Why, we-er-am scratching for it."-Chicago Druggist.

BALSAM OF PERU IN THE TREATMENT OF OZÆNA.-Practitioners who see much of ozæna know well that it is one of the most intractable diseases. Even with the frequent washing out of the nasal passages with antiseptic lotions and sprays, with medicated bougies, and with cotton-wool plugs applied in the manner recommended by Gottstein, only the most transitory deodorization of the breath from the nostrils can be effected, and patients and their friends are driven almost to despair. Any new suggestion for the relief of this disgusting complaint will therefore be welcomed. Dr. W. Ebstein has lately reported very satisfactory results obtained by Dr. Rosenbach with balsam of Peru. The mucous lining of the nasal fossa is painted every day with the medicament,

and a plug of cotton wool soaked in it is left in the deep parts of the nose. By this means Dr. Rosenbach has succeeded in cases in which every other antiseptic and deodorizer had been tried in vain. It is not probable, however, that experienced practitioners, who have often been disappointed with the effect of the most promising suggestions for the cure or mitigation of ozæna, will be disposed to pin their faith too tightly on any new remedy, more especially, perhaps, in the case of Peruvian balsam, which seems just at present in some danger of becoming a panacea in the hands of some of our German brethren.-London Med. Recorder.

FORMULE FOR CORNUTIN.-Cornutin, the new uterine hæmostatic, may be given either by the mouth or hypodermically. The following formulæ are recommended by the Journal de Médecine de Paris, June 16:

I. For hypodermic injection.
R.-Cornutin

Distilled water

Hydrochloric aid

Sig. One syringeful for an injection.

II. In pill form.

R.-Cornutin

Gum arabic paste

Make into twenty pills. Sig. Two or three at a dose.

THE CONSTRUCTION OF A NEW BLADDER AFTER EXCISION. -At the Surgical Congress recently held at Bologna, Professor G. Tizzoni, of the University of that city, and A. Poggi gave an account of some experiments they had made on dogs, with the view of ascertaining whether the bladder could be removed and an efficient substitute constructed by operation. First of all laparotomy was performed, and a loop of small intestine about seven centimetres in length, with its mesentery attached, was isolated by two transverse cuts, washed out with a carbolized solution, and tied at both ends, one extremity being fixed in front of the neck of the bladder. The two ends of the divided gut were then stitched accurately together by circular suture. The dog soon recovered from the operation, and a month later the second stage of the experiment was performed. The ureters were separated from the bladder, and the latter was completely removed. The loop of intestine destined to be the new bladder was then cut across at the lower end and stitched to the neck of the bladder. The ureters were then turned into the

artificial bladder. A slender elastic drainage-tube was placed in the urethra to carry off the urine during the first few days. The animal recovered perfectly, and gradually acquired control over its new bladder, and when shown to the Congress, two months later, showed no sign of incontinence. The operation has been repeated with success on several other animals, and Drs. Tizzoni and Poggi are hopeful that it may be applicable to the human subject. — Medical Recorder.

TREATMENT OF HICCOUGH.-Dr. John I. Brinkerhoff, of Auburn, N. Y., writes to the New York Medical Journal of July 6th, that he has found calamus a remedy for hiccough in every case in which he has used it, including some cases of an aggravated character. A very small quantity suffices, only enough to reach the throat when dissolved by the saliva.

NEW SKIN REMEDIES. -Schwimmer has lately, in the Wiener Medizinische Wochenschrift, published the results he has obtained in certain skin diseases by the use of salol, oxynaphtheic acid, salicylate of mercury, and anthrarobin. Salol mixed with starch in the proportion of two to one he finds a very effective remedy in all forms of venereal sores and in the buboes resulting from them. Iodoform seems to have a more rapid action, but salol has the superiority of possessing no smell. The drug also appears useful in conditions of the mucous membrane of the bladder, when given internally in doses of forty-five to ninety grains distributed through the day. Oxynaphthoic acid did not give good results in venereal cases, acting as an irritant. In scabies, however, it did not irritate, and was an effective remedy. It may be mixed with chalk and soft soap, each ten per cent., with lard. It acted well also in the secondary eczema of scabies, and allayed itching in prurigo. Salicylate of mercury possesses no superiority over the ordinary remedies used in gonorrhoea and venereal sores. Given internally in doses of one and a half to two grains, it was an effective anti-syphilitic drug, although apt to cause irritation of the intestine and stomatitis. Anthrarobin was found to have no beneficial effect in psoriasis, but in herpes tonsurans, eczema marginatum, and pityriasis versicolor it acted well, being mixed with collodion in the strength of one to ten.—British Medical Journal, June 29, 1889.

BILIOUS ATTACKS.-The bilious attacks occurring in neurotic individuals are very different paroxysms from those seen in habitual or occasional overfeeders. A clean tongue -often "geographical" or desquamating too freely in patches-a scanty, high-colored lithatic urine, a sallow face, white motions, dilated pupils, low spirits, and absence of energy, constitute the clinical entity in many cases of bilious attacks. These are very common in neurotic children with dainty appetites, in whom to suppose that irritation and vascular engorgement of the viscera, from overfeeding, exist, would be ridiculous. A sharp purge to these patients may do more harm than good, though it is possible to set the Viscera working again by such sudden means. An inadequate liver may be the cause of a toxemia, and the poison in the blood may have a selective action on the mental centers, originating lowness of spirits, melancholia; this is the view most favored by the laity, but it is often incorrect. In truth, a mutual tension between the viscera and the brain exists-reciprocity rules the realms of the human body as it does the social organism. The truth appears to be that the viscera may go wrong as the result of being undercharged with nervous energy, and they simply cease to work effectively because of defective nervous energization. The correct treatment is not a dose of castor oil, but a tablespoonful of wine at once, and a tablespoonful of syrup of the hypophosphites three times every day for one week. -Angel Money, in Lancet.

QUININE IN CHOLERA. —Dr. Lawrie, the Residency Surgeon in Deccan, asserts that quinine in three to five grain doses three times a day is an efficient preventive of cholera.

MASSAGE OF ABDOMEN AND LUMBAR REGION AS A DIURETIC. -Dr. Polubinski reports his observations of massage on the abdomen and lumbar region made with a view of ascertaining its physiological action on the kidneys. The subject, upon whom he experimented were healthy persons, and they received the same quantity of food. The experiment commenced at 12 (noon), when the subjects (ten in number) urinated, and the urine thrown away. The urine of twentyfour hours was collected in different vessels as follows: First portion from 12 to 2 P. M. (in massage days: dinner, half hour; massage, half hour and one hour rest); second portion, from 2 to 4 P. M. (massage, half hour; one and a half hour rest),