Signaling Through Cell Adhesion Molecules
The field of signal transduction research is one of the fastest growing in all of biomedical research in recent years. Signaling through cell adhesion molecules have long been of interest because of their importance in embryonic development, homeostasis, immune responses, wound healing , and malignant transformation. However, it is only recently realized that cell adhesion molecules are capable of transduce biochemical signals across the plasma membrane to regulate cellular functions.
Signaling Through Cell Adhesion Molecules brings together novel and current methodology employed in studies of signaling by cell adhesion molecules as presented by leading experts whose research has shaped this nascent area of signal trandsduction research.
One of the unique features of this method book is its topic-oriented format; experts with "hands-on" experience present various techniques and answers to particular biological questions. Many chapters not only contain the "recipes" on experimental protocols, but also discuss the rationale behind their development.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Late Events and Biological Functions of Integrin Signaling
InsideOut Signaling by Integrins
General Methods for Signaling Studies of Cell Adhesion Molecules
Intra and Intercellular Localization of Proteins in Tissue in situ
Methods for Studying Anoikis
Other editions - View all
3-catenin activation analysis assay axis beads binding blocking cDNA cell adhesion Cell Biol cellular centrifugation Chem chimeric receptors CHO cells clones containing coverslips culture cytoplasmic cytoplasmic domains cytoskeletal detected dilution dishes DMEM dorsal EDTA electroporation embryos endogenous expression extracellular fibroblasts fibronectin fibronectin matrix assembly filter flow cytometry fluorescence focal adhesion kinase fusion protein gene growth factor immunoblotting immunofluorescence immunoprecipitation incubated induce inhibit inhibitors integrin integrin signaling integrin-mediated interaction lysis buffer medium membrane mesoderm mg/ml microfuge microscope Molecular molecules monoclonal antibody mRNA myoblasts myosin NaCl paxillin pellet peptide pg/ml phenotype phosphorylation plasmid plate protocol reagents regulate resuspended room temperature sample SDS-PAGE secondary antibody Section serum Sigma signal transduction signaling pathways solution specific staining stress fibers subunit supernatant tissue transfected transfected cells trypsin tube tyrosine kinase tyrosine phosphorylation ventral washed Western blotting Wnt pathway Xenopus