The Cellular Basis of Cardiovascular Function in Health and Disease

Front Cover
Pawan K. Singal, Vincenzo Panagia, Grant Pierce
Springer Science & Business Media, Dec 31, 1997 - Science - 353 pages
This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.
 

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Contents

VASCULAR CHANGES IN HEALTH AND DISEASE
3
Analysis of responses to human synthetic adrenomedullin and calcitonin generelated peptides in the hindlimb vascular bed of the cat
5
Intimal hyperplasia reendothelialization and attenuation of endothelialdependent relaxation
13
Differential regulation of Gprotein expression by vasoactive peptides
21
Receptor types and Ca2+mobilization
29
Activation of the neutrophil and loss of plasma glutathione during Mgdeficiency modulation by nitric oxide synthase inhibition
35
Velocity of translation of single actin filaments AF by myosin heads from antigensensitized airway smooth muscle
41
Smooth muscle contractility and protein tyrosine phosphorylation
47
SUBCELLULAR CHANGES IN CARDIOMYOPATHIES AND HEART FAILURE
165
Changes in fatty acid compositions of myocardial lipids in rats with heart failure following myocardial infarction
171
Mechanisms that may be involved in calcium tolerance of the diabetic heart
183
Increases of Ttype Ca2+ current in heart cells of the cardiomyopathic hamster
191
Influence of beta blocking agents
197
Phosphorylation by protein kinase C and the responsiveness of Mg2+ATPase to Ca2+ of myofibrils isolated from stunned and nonstunned porcine m...
203
Is there a link between impaired glucose metabolism and protein kinase C activity in the diabetic heart?
211
Experimental myocardial infarction in rats in vivo with reduced mortality
219

Migration of heterogeneous cell populations from vessel wall
53
An overview of the influence of ACE inhibitors on fetalplacental circulation and perinatal development
61
CARDIAC MECHANISMS IN HEALTH
73
Differential nature of crosstalk among three Gcoupled receptors regulating adenylyl cyclase in rat cardiomyocytes chronically exposed to receptor ag...
75
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone UDCG 212 CL in myofilaments from human ventricle
83
Expression of fibroblast growth factor receptor1 in rat heart H9c2 myoblasts increases cell proliferation
89
Identification of an HMGlike protein involved in regulation of Na+H+ exchanger expression
99
Cytochemical and immunocytochemical localization of NaKATPase α subunit isoenzymes in the rat heart
107
Estradiol modulates the sodium pump in the heart sarcolemma
113
Thyroid hormones differentially affect sarcoplasmic reticulum function in rat atria and ventricles
118
Dietary and physiological studies to investigate the relationship between calcium and magnesium signalling in the mammalian myocardium
125
Biological significance of phosphorylation and myristoylation in the regulation of cardiac muscle proteins
133
Contributions of increased efficiency and capacity of protein synthesis to rapid cardiac growth
143
Movement from chromosomal to cleavage furrow and midbodyassociated sites
151
Its effects on sarcoplasmic reticular SR Ca2+ metabolism
161
Adriamycin depresses in vivo and in vitro phosphatidylethanolamine Nmethylationin rat heart sarcolemma
227
A calcium stimulated cysteine protease involved in isoproterenol induced cardiac hypertrophy
233
Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster
241
Na+H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemiareperfusion 31P NMR studies
245
Increased gene expression of plasminogen activators and inhibitors in left ventricular hypertrophy
253
Old concepts new perspectives
261
Effect of diabetes mellitus
269
Cardiomyopathies and mitochondrial DNA mutations
275
Role of free radicals
279
Ischemic preconditioning is not additive to preservation with hypothermia or crystalloid cardioplegia in the globally ischemic rat heart
291
CELLULAR BIOCHEMISTRY IN NONCARDIOVASCULAR TISSUES
303
Regulation of Ca2+ homeostasis by glucose metabolism in rat brain
305
LAcp corpulent rat
313
Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion
321
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