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According acid action activity acts administration alcohol alkaloid amount anesthesia animals appears applied arrest arterial asserted atropine becomes believes blood body cardiac cause cent centres changes chloroform chronic circulation cocaine complete condition confirmed contains contraction convulsions death depressant digitalis dilatation direct disease doses drug effect elimination employed especially ether evidence excitement experiments fall fatal finally followed four frequently frog given grains heart hypodermically increase indicate influence injection irritation large doses less lessening lower marked minutes motor muscles muscular nerves nervous normal observers obtained occurs opium pain paralysis paralyzed patient peripheral physiological poisoning practical preparations present pressure probably produced pulse pupil quinine rapid reflex remedy reported respiration respiratory rise salts seems shown skin slow soluble solution sometimes spinal cord stage stimulant stomach strychnine substance sufficient symptoms taken temperature tion toxic urine usually various violent vomiting Wood
Page 614 - Carrageen, being demulcent and nutritious, is employed as an article of diet in those cases requiring food of such character, and may be used instead of arrow-root. It is to be prepared by first soaking for ten minutes in cold water, and then boiling from half an ounce to an ounce of it (according to the desired consistency) in a pint and a half of water down to a pint, sweetening and flavoring to taste.
Page vi - ... teaching that to bleed a man suffering from pneumonia is to consign him to a grave never opened by nature. Looking at the revolutions and contradictions of the past, listening to the therapeutic babel of the present, is it a wonder that men should take refuge in nihilism, and, like the lotus-eaters, dream that all alike is folly; that rest, and quiet, and calm are the only human fruition...
Page 353 - ... disorders of the skin appear. Of these, herpes zoster seems to be the most frequent; it probably is the result of an arsenical neuritis. Another common skin affection is erythromelalgia, the painful red swelling of the epiderm. In protracted cases there is frequently thickening of the horny tissue in the palms of the hands and soles of the feet, which occasionally extends up the limb. The formation of transverse ridges across the nails, the result of the hyperkeratosis, has also been noted. The...
Page vii - Niemeyer's assertion, that experiments made with medicaments upon the lower animals or upon healthy human beings have, as yet, been of no direct service to our means of treating disease, and that a continuation of such experiments gives no prospect of such service, it is certain that in these experiments is the only rational scientific groundwork for the treatment of disease. We must discover what influence a drug exerts when put into the body of a patient before we can use it rationally; and we...
Page vi - Experience is said to be the mother of wisdom. Verily she has been in medicine rather a blind leader of the blind; and the history of medical progress is a history of men groping in the darkness, finding seeming gems of truth one after another, only in a few minutes to cast each back to the vast heap of forgotten baubles that in their day had also been mistaken for verities. In the past, there is scarcely a conceivable absurdity that men have not tested by experience and for a time found to be the...
Page 523 - To soothe and diminish irritation of tlie genito-urinary organs. The value of water in fulfilling this and the next indication has already been pointed out. By lessening the acidity of the urine and rendering soluble the uric acid which is present, the alkalies are equally important in carrying out the present and the following indication. 4. To alter the urinary secretion so as to prevent the deposition of calculous material. Notwithstanding it has been...
Page 160 - ... inhaled by a man in moderate quantities, are a sense of great fulness and distention of the head, amounting at last to severe pain, and accompanied by intense flushing of the face, a deep, labored respiration, and an exceedingly rapid, violent action of the heart. The succession of these phenomena is so rapid that often they seem to be simultaneous ; but it is said that the cardiac disturbance is sometimes very distinctly manifest before the other symptoms.
Page 486 - Duckworth especially noted intense hyperaemia of the lungs, which were in some places emphysematous, but in other portions collapsed and even affected with true consolidation. The lesions were much less marked in the intestines than in the lungs, which resembled very closely those taken from the bodies of animals killed by section of the vagi. The pulmonic lesions were found to be most intense in the rabbit ; the intestinal, in the dog, cat, and guinea-pig.
Page vii - Evidently, it is his especial province to find out what are the means at command, what the individual drugs in use do when put into a human system. It is seemingly self-evident that the physiological action of a remedy can never be made out by a study of its use in disease.
Page 505 - The low diffusibility of the salt impedes the absorption of the secreted fluid. 4. Between stimulated secretion on the one hand, and impeded absorption on the other, there is an accumulation of fluid in the canal. 5. The accumulated fluid, partly from ordinary dynamical laws, partly from a gentle stimulation of the peristaltic movements excited by distension, reaches the rectum and produces purgation.