Response Variability to Psychotropic DrugsW. Janke |
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Page 23
... psychoactive drugs in the human increased enzyme synthesis by enzyme inducers is of greater clinical relevance than enzyme inhibition . The best known and most potent stimulators are phenobarbitone and other barbiturates , which have ...
... psychoactive drugs in the human increased enzyme synthesis by enzyme inducers is of greater clinical relevance than enzyme inhibition . The best known and most potent stimulators are phenobarbitone and other barbiturates , which have ...
Page 27
... psychoactive drug blood levels and clinical response : CPZ , meperidine and thioridazine . Psycho- pharm . Bull . , 9 , 40-43 . Gottschalk , L. A. , R. Biener , E. P. Noble , H. Birch , P. E. Wilbert , and J. F. Her ( 1975 ) ...
... psychoactive drug blood levels and clinical response : CPZ , meperidine and thioridazine . Psycho- pharm . Bull . , 9 , 40-43 . Gottschalk , L. A. , R. Biener , E. P. Noble , H. Birch , P. E. Wilbert , and J. F. Her ( 1975 ) ...
Page 28
... drugs in man . In D. S. Davies , and B. N. C. Prichard ( Eds . ) , Biological Effects of Drugs in Relation to their Plasma Concentrations . University Park Press , Baltimore . pp . 83-95 . Lin , K. M. , and R. O. Friedel ( 1979 ) ...
... drugs in man . In D. S. Davies , and B. N. C. Prichard ( Eds . ) , Biological Effects of Drugs in Relation to their Plasma Concentrations . University Park Press , Baltimore . pp . 83-95 . Lin , K. M. , and R. O. Friedel ( 1979 ) ...
Contents
Some basic principles and their influence | 3 |
Drug Response Variability Overview of Contributing Factors | 31 |
Debus | 62 |
Copyright | |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavior chlordiazepoxide chlorpromazine cigarettes smoked Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response drug tolerance effects of drugs emotional responses environmental enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone human imipramine increase individual differences influence interaction introverts investigation iproniazid Janke Lehmann and Hopes Lienert lofepramine male measures ment meprobamate MHPG neurotic neuroticism nicotine normal observed orciprenaline oxprenolol performance pharmacokinetic Pharmacol pharmacological physiological placebo placebo group plasma levels posttreatment prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological Psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold self-medication significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table therapeutic tion tranquilizer treatment Warburton Wesnes Wittenborn