Response Variability to Psychotropic DrugsW. Janke |
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Page 238
... placebo comparisons . These placebo comparisons must be conducted under the familiar conventions of random assign- ments of either the drug in question or an indistinguishable placebo . The subjects should be drawn from a relatively ...
... placebo comparisons . These placebo comparisons must be conducted under the familiar conventions of random assign- ments of either the drug in question or an indistinguishable placebo . The subjects should be drawn from a relatively ...
Page 255
... Placebo and ECT Groups Variables ( n = 97 ) Depression Phobia Paranoia ( state ) Suicidal ( state ) Displacing ( trait ) -.22 Self - critical ( trait ) * ECT or Placebo -.29 .23 Anxiety -.31 -.37 * Biserial correlations ; a negative ...
... Placebo and ECT Groups Variables ( n = 97 ) Depression Phobia Paranoia ( state ) Suicidal ( state ) Displacing ( trait ) -.22 Self - critical ( trait ) * ECT or Placebo -.29 .23 Anxiety -.31 -.37 * Biserial correlations ; a negative ...
Page 281
... placebo Fig . 2 . Adjusted cell means for heart rate . left side : simple effects of drugs under the three situational conditions . right side : simple effects of the situational con- ditions under placebo . ox = oxprenolol , pl = placebo ...
... placebo Fig . 2 . Adjusted cell means for heart rate . left side : simple effects of drugs under the three situational conditions . right side : simple effects of the situational con- ditions under placebo . ox = oxprenolol , pl = placebo ...
Contents
Some basic principles and their influence | 3 |
Drug Response Variability Overview of Contributing Factors | 31 |
Debus | 62 |
Copyright | |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavior chlordiazepoxide chlorpromazine cigarettes smoked Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response drug tolerance effects of drugs emotional responses environmental enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone human imipramine increase individual differences influence interaction introverts investigation iproniazid Janke Lehmann and Hopes Lienert lofepramine male measures ment meprobamate MHPG neurotic neuroticism nicotine normal observed orciprenaline oxprenolol performance pharmacokinetic Pharmacol pharmacological physiological placebo placebo group plasma levels posttreatment prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological Psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold self-medication significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table therapeutic tion tranquilizer treatment Warburton Wesnes Wittenborn