Response Variability to Psychotropic DrugsW. Janke |
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Page 22
... observed in most samples of patients . ( 2 ) The role of age in drug metabolism has been investigated and re- viewed by several authors with respect to the developing organism as well as to old age ( Stevenson , 1973 ; Davies and ...
... observed in most samples of patients . ( 2 ) The role of age in drug metabolism has been investigated and re- viewed by several authors with respect to the developing organism as well as to old age ( Stevenson , 1973 ; Davies and ...
Page 75
... observed in adult rats that had been treated with 6 - hydroxy- dopamine and desmethylimipramine between days 3 and 14 of life , an effect which was not observed if treated on days 20 or 23 of age ( Erinoff and others , 1979 ) . Deviant ...
... observed in adult rats that had been treated with 6 - hydroxy- dopamine and desmethylimipramine between days 3 and 14 of life , an effect which was not observed if treated on days 20 or 23 of age ( Erinoff and others , 1979 ) . Deviant ...
Page 103
... observed incidence in a random sample of the popula- tion . The operation of genetic factors is suggested when disconti- nuities in effects are observed - when subgroups within the population sampled are found to have significantly ...
... observed incidence in a random sample of the popula- tion . The operation of genetic factors is suggested when disconti- nuities in effects are observed - when subgroups within the population sampled are found to have significantly ...
Contents
Some basic principles and their influence | 3 |
Drug Response Variability Overview of Contributing Factors | 31 |
Debus | 62 |
Copyright | |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavior chlordiazepoxide chlorpromazine cigarettes smoked Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response drug tolerance effects of drugs emotional responses environmental enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone human imipramine increase individual differences influence interaction introverts investigation iproniazid Janke Lehmann and Hopes Lienert lofepramine male measures ment meprobamate MHPG neurotic neuroticism nicotine normal observed orciprenaline oxprenolol performance pharmacokinetic Pharmacol pharmacological physiological placebo placebo group plasma levels posttreatment prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological Psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold self-medication significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table therapeutic tion tranquilizer treatment Warburton Wesnes Wittenborn