quite disappeared. It would be rash to conclude too much from these results, in the face of the intractability of neuralgiæ to medication, but if it really prove to be as efficacious as considered, hyperosmic acid will be a therapeutic agent of no mean value.— Halls' Journal of Health. Gonorrhoea-Potash Chlorate. Dr. J. Milton, in the N. Y. Med. Record, states that he has had excellent results from the internal use of the following mixture in ordinary cases of gonorrhoea: Potash chlorate, two drachms; boiling water, four ounces. Mix, and shake till solution is accomplished; then add potass. acetat, two drachms; spirits of juniper, four drachms; camphor mixture, six ounces. M. S. Dose, a teaspoonful twice daily.-Chic. Med. Times. Monobromide of Camphor. Monobromide of camphor is one of our best remedies for spermatorrhoea. In therapeutic action it is allied to the bromides. Dr. H. C. Wood has given it with benefit in cases of convulsions, whooping-cough, hysteria and asthma. It may be given in doses of five or ten grains every three or four hours. It is not easy to obtain in "solution," and is best administered in the form of capsuled pills.-Med. Bulletin. Rheumatism. According to the report of practice at the Bellevue Hospital, it is stated that for controlling pain in fibrous tissue, belladonna, and stramonium ointments were far more serviceable than opium, and that in acute articular rheumatism the following was strongly recommended: Hydrate of chloral, 1 drachm; salicylic acid, drachm; stramonium ointment, 1 ounce. Mix.Druggist's Circular. Warts of the Genitals. Dr. Cadell says that warts of the genitals treated with chromic acid in the proportions of 100 grains to one ounce of water, disappear with marvelous rapidity and with but little pain.-Louisville Med. News. Obituary. T. N. Waterbury, M. D., of Westerville, Neb., died of typhoid fever, September 21st, 1884. Dr. Waterbury was born January 24th, 1857, graduated in The American Medical College in 1883, and was in a fair way to earn a famous reputation when he was called away. He leaves an excellent wife and two children, besides hosts of friends to mourn his loss. He was highly respected by all the professors, as well as by his classmates while at college, and our community lost a valuable, worthy and much respected citizen when he died. J. N. PEAL. PROFESSIONAL AND BUSINESS EXCHANGE. Under this head notices for sale or exchange, locations, or partnerships wanted, and other notices of like nature, will be inserted at $2 a time. If more than eight lines, 25 cents extra for each additional line. Always in advance. Wanted. Two well-educated experienced Eclectic physicians, of means, to locate in the city of St. Louis. If of the right stamp they might get places in the American Medical College. Address the Editor, GEO. C. PITZER, M. D., St. Louis, Mo. Vaccine Virus. All orders for fresh and reliable animal vaccine should be addressed R. M. HIGGINS, M. D., Webster Groves, Mo. Missouri Vaccine Farm, 5 quills, 10 vaccinations, $1.00; 10 points, 10 vaccinations, $1.00; 1 extra crust, $3.00. Medical Books and Surgical Instruments. We make a specialty of the Book Business. Students and practitioners wanting books of any kind, no matter of what school or where published, may order them direct from us, and rely upon getting what they want, and upon as good terms as they can be had anywhere. Surgical Instruments, Pocket cases, and Saddle-bags the same. For price list see advertising page v. Galvanic Batteries and Electrical Instruments a specialty. Can furnish the best in the market. Journal Business. Address, GEO. C. PITZER, M. D., 1110 Chambers Street, St. Louis, Mo. The regular subscription of this journal is $2.00 a year, in advance. ART. XIII.-Eczema.-BY PROF. E. YOUNKIN, M. D. Eczema is a non-contagious vesicular inflammation of the skin. It is one of the most frequent, most obstinate, and certainly the most important of all the cutaneous affections. It presents by an eruption of vesicles, not prominent, but closely set together, and the vesicles exude-" boil out" a limpid fluid, which, if not re-absorbed, dries up, leaving flakes, scales and crusts. Although, commonly, it appears in patches or is confined to a single district, yet it may present simultaneously or successively in different parts, or cover the greater part of the entire body. Eczema has an affinity for those parts where the follicles are numerous, as the hairy scalp, the ears, more rarely the face, the roots of the nails, and backs of the hands. In children it particularly affects the hairy scalp, ears and eyelids; in the adult male, the inner parts of the thighs, scrotum and verge of the anus; and in women it is likely to develop on the nipples, vulva and rectum. The disease may be either acute or chronic, and it presents many phases, varying with the stage, character of the primitive lesion, degree of inflammatory action, individual peculiarities, complicating circumstances, etc. An outbreak of eczema commences with a prodromal period of local heat, redness and slight swelling, and certain subjective sensations which attract attention to the parts. From first appearances alone it will be hard to decide what form of cutaneous disease is impending, just as during the first day of active febrile movement we may be unable to predict the character of the disease that will be developed on the morrow. Among children the process of teething and the quality of the food seem to be an assignable cause; in women, amenorrhoea and dysmenorrhoea frequently exert a notable influence; but in many cases we are unable to give any reasonable cause for the outbreak, and we are forced to conclude that eczema is evolved by some hidden alteration of the fluids and solids. There is strong presumptive evidence that eczema is caused from some disorder of the renal function. Indican is found to be present in the urine of eczematous patients, and it is supposed to be due to retardation of the products of function and secretion. Others have suggested that the disease may be due to a parasite, but the present state of our knowledge leaves the question of causation unsettled. Eczema may present in one of three different varieties: 1st-Eczema Simplex; 2d-Eczema Rubrum; and 3d-Eczema Impetiginodes. 1.-Eczema Simplex is a mild variety; the affected parts are covered with minute vesicles, with but slight change in the color of the skin. The active congestion may give place to a more passive form of indefinite duration characterized by slight redness, with an occasional moisture alternated with dryness, after which appears a fine desquamation. The congestion is usually attended with a moderate amount of heat and itching, and when scratched a small quantity of serous fluid escapes, which, when dried, leaves the cuticle detached in minute flakes or scales, and at this stage a new crop of vesicles appears. Eczema Simplex may extend over the whole body, especially in children that are irritable, poorly fed, and have bad hygiene surroundings. 2.-Eczema Rubrum is, very intense. As its name implies (red eczema), the heat, redness and tension are exaggerated, and may continue for many days or weeks. The vesicles are evolved and burst with great rapidity; the fluid that escapes irritates and excoriates the parts with which it comes in contact. The skin stripped of its cuticle is beset with a multitude of pores, from whence exudes a reddish colored fluid, sometimes in such profusion as to soak the clothing, and after the torrent of serum the sub-epidermic layer may present scales of false membrane of a whitish color, which becoming detached falls off and another membrane takes its place. As the disease advances the parts lose their redness and tension, and either recover or pass into a more chronic form. 3.-Eczema Impetiginodes is a compound of two diseasesof eczema and impetigo. Each of these in its separate state has its own elementary character-a vesicle in eczema and a pustule in impetigo. In eczema impetiginodes we have both the vesicle and pustule, the vesicle, however, being the primary element and generally predominating. It often happens that we find a mixture of vesicle and pustule covering the greater part of the body, the vesicles becoming purulent, and the distress in proportion to the stage, as to whether acute or chronic. Thus it must be remembered that the three acute forms now described may present shades of extreme variety, and when extended over a large amount of surface the disease is accompanied with disturbed action of a general nature-the pulse frequent, thirst, anorexia aud disturbed sleep. The most common complications are inflammations and indurations of the lymphatic glands in the vicinity of the affection of the skin, and among children disorders of the digestive organs. Any of the above forms may pass from their acute stage to the chronic forms, in which the skin becomes dried, cracked and fissured, or the exudation may form large scabs. The crusts often cover the entire surface of the parts affected, and form the familiar picture known as crusta lacta, milk scurf, porrigo larvalis, melitagra flaveseins or nigrecans. A common nomenclature of eczema is that according to the location of the disease, as, 1.-Eczema of the Scalp.-This form is frequently found among children at the breast, and is often classed with the tineas and porrigos. It is found in all stages, from the simple roughening of the skin to the rubrum, madidum and squamosum. The impetiginous variety, however, is the most common. The |