ENTERED, according to Act of Congress, in the year 1876, by

D. APPLETON AND COMPANY,

In the Office of the Librarian of Congress, at Washington.

CONTRIBUTORS TO VOLUME XXIII.

BERMINGHAM, EDWARD J., LUSK, WILLIAM T., M. D.

BILLINGS, JOHN S., M. D., U. MASON, JOHN J., M. D.

BONTECOU, R. B., M. D., Troy, MOSES, M. J., M. D.

BRADFORD, E. H., M. D., Boston, OTIS, FESSENDEN.N., M. D.

PAGE, R. A., M. D., Washington,
D. C.

PALLEN, MONTROSE A., M. D.
PATTON, G. FARRAR, Bonn,
Prussia.

BYRD, WILLIAM A., M. D., Quin- PIFFARD, HENRY G., M. D.

cy, Ill. CHAMBERLAIN, WILLIAM M., POORE, C. T., M. D.

POOLEY, THOMAS R., M. D.

KEYT, A. T., M. D., Cincinnati, O. VAN DE WARKER, ELY, M. D.,

ART. I.-Remarks on Chronic Dysentery; with the History

of a Case of Five Years' standing cured within Five

Weeks by Topical Treatment. By T. GAILLARD THOMAS,

M.D.

THERE are few curable diseases which offer a more unfa-
vorable prognosis than chronic dysentery. The dangers which
attend the affection in its acute stage are greatly increased in
that in which painful, hæmorrhagic, and intractable ulcers
cover the surface of the rectum and colon, and exhaust the
patient by loss of blood, constant pain, frequent evacuations,
and the intense nervous depression which attends such cases.

The experienced practitioner will require no citation of
authorities to remind him of the determined hold which this
disease keeps upon the individual once becoming affected by
it; how it baffles all varieties of medical treatment; and how
for years it pursues its victim, and in spite of change of air
and of all his habits of life it goes on to a fatal issue. So re-
morseless is its course, and withal so uniform, that it justifies
this description at the hands of a modern writer: "Chronic