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Injury to the vessel lining and contact of the blood with tissues outside the vessel
stimulates thrombin production by the activation of the clotting system. Thrombin
causes platelet aggregation. Platelets exposed to thrombin secrete their ...
Plasma, anticoagulated with citrate buffer, is allowed to clot with the simultaneous
addition of phospholipid, calcium, and thromboplastin. The duration of time until
clot formation, known as the prothrombin time, is usually between 10 and 12 ...
bolism (clots in the lung) and deep vein thrombosis (clots in the leg veins). Other
predisposing causes of thrombosis are an increase in platelet numbers in the
blood and the formation of functionally abnormal platelets in diseases of the bone
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