Stealth LiposomesThis book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans. |
Contents
Chapter | 1 |
Chapter | 13 |
Chapter 5 | 35 |
Chapter 6 | 51 |
Modulation and Modeling of Interaction Forces between | 73 |
Chapter 9 | 93 |
Biological Properties of Sterically Stabilized Liposomes | 103 |
Chapter 11 | 119 |
Chapter 14 | 143 |
Chapte 15 | 173 |
Chapter 16 | 187 |
Chapter 18 | 211 |
Chapter 20 | 233 |
Chapter 21 | 245 |
Chapter 23 | 267 |
| 283 | |
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Common terms and phrases
accumulation Acta adsorbed adsorption Allen amphotericin antibody ara-C Biochim Biophys brush Cancer Res carcinoma cells cholesterol clearance colloidal compression concentration conventional liposomes density dose DOX-SL Doxil doxorubicin drug delivery DSPE effect efficacy encapsulated entrapped epirubicin FEBS Lett Figure formulations free drug Gabizon Gennes glycol glycolipids grafted polymer Gregoriadis half-life headgroups hepatocytes Huang immunoliposomes implanted increased injection interaction interface Kaposi's sarcoma Lasic lipid bilayer lipid composition liposome surface Liposome Technology liposomes containing liver long circulating liposomes lung Macromolecules macrophages Martin Mayhew membrane mg/kg mg/m² mice molecules mouse mushroom opsonins opsonization Papahadjopoulos particles patients PEG-lipid PEG-PE pharmacokinetics phosphatidylcholine phospholipid plasma polyethylene polyethylene glycol polymer polymer chains polymer-lipid pressure prolonged circulation proteins rats receptors repulsion reticuloendothelial system S-VCR Stealth liposomes steric barrier sterically stabilized liposomes studies target therapeutic therapy tissue Torchilin toxicity treatment tumor unilamellar liposomes uptake vesicles vincristine vivo Woodle