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The Best Antiseptic for Both Internal and External Use.

LISTERINE.

Antiseptic, Prophylactic, Deodorant, Non-Toxic Non Irritant, Non-Eseharotic, Absolutely Safe, Agreeable, and Convenient.

FORMULA.-Listerine is the essential antiseptic constituent of Thyme, Eucalyptus, Baptisia, Gaultheria, and Mentha Arvensis, in combination. Each fluid drachm also contains two grains of refined and purified Benzo-boracic Acid.

DOSE.-Internally: One teaspoonful three times or more a day (as indicated), either full strength or diluted, as necessary for varied conditions.

Listerine is a well-proven antiseptic agent-an_antizymotic-especially adapted to internal use and to make and maintain surgical cleanliness-asepsis-in the treatment of all parts of the human body, whether by spray, irrigation, atomization, or simple local application, and therefore characterized by its particular adaptability to the field of

Preventive Medicine-Individual Prophylaxis.

With its certain antiseptic and prompt deodorant properties, LISTERINE combines a mild stimulating influence (easily graded by dilution), free from irritating effects. It quickly loosens tenacious mucous secretions, and the boracic acid, being in perfect solution, is, by means of the spray, readily conveyed to and deposited upon the innermost recesses of the air passages.

In union with alteratives, resolvents and astringents, LISTERINE fills many requirements of the Laryngologist. We have much valuable literature bearing upon diseased conditions of the upper air passages to forward to those physicians who request it.

LAMBERT PHARMACAL COMPANY,

SAINT LOUIS.

SCOTT'S EMULSION

VERSUS

PLAIN COD LIVER OIL.

Plain Cod Liver Oil is indigestible, deranges the stomach, destroys the appetite is not assimilated, and in a majority of cases is detrimental to the patient.

SCOTT'S EMULSION

Can be digested in nearly all cases, is assimilated, does not derange the stomach, nor overtax the digestive functions, and can be taken for an indefinite period when the plain cod liver oil cannot be tolerated at all, and with most marked results in Anæmia, Consumption and all wasting conditions. It also contains the Hypophosphites of Lime and Soda with Glycerine, which are most desirable adjuncts.

WHEN PHYSICIANS TRY IT THEY INVARIABLY USE IT

in preference to the plain cod liver oil or other so-called Emulsions that invariably separate, and hence their integrity and value is destroyed. Scott's Emulsion is palatable and absolutely permanent hence its integrity is always preserved.

The formula for SCOTT'S EMULSION is 50 per cent. of the finest Norwegian Cod Liver Oil, 6 grains Hypophosphite of Lime and 3 grains Hypophosphite of Soda to the fluid ounce, Emulsified, or digested to the condition of assimilation with chemically pure Glycerine and Mucilage.

We also wish to call your attention to the following preparations:

CHERRY MALT PHOSPHITES.

A combination of the tonic principles of Prunus Virginiana, Malted Barley, Hypophosphites of Lime and Soda, and Fruit Juices. An elegant and efficient brain aud nerve tonic.

BUCKTHORN CORDIAL (Rhamnus Frangula).

Prepared from carefully selected German Buckthorn Bark, Juglans Bark and Aromatics. The undoubted remedy for Habitual Constipation.

Be sure and send for samples of the above delivered free.

SCOTT & BOWNE, 132 South Fifth Avenue, NEW YORK.

ALEXANDER W. MacCOY, M.D.,
Professor of Diseases of Throat and Nose, Philadelphia Polyclinic and
College for Graduates in Medicine.

THE MALTINE MANUFACTURING CO.

Gentlemen:

Writes

"MALTINE WITH HYPOPHOSPHITES" is a very satisfactory compound when the system requires not only fat-making material, but bone-making matter as well, and the form in which you have it renders the hypophosphites readily digested, while the combination quickly enriches the blood and restores the normal equilibrium of nutrition. In the treatment of chronic nasal catarrh, enlarged tonsils, chronic bronchitis, affections of the voice, etc., where a reconstructive is so often called for in conjunction with local treatment, "MALTINE WITH HYPOPHOSPHITES" has proved very prompt and beneficial.

The preparation is so pleasant to the taste that the taking of it becomes an agreeable rather than a distasteful duty.

Philadelphia, Pa., April 25th, 1890.

Very truly yours,

ALEXANDER W. MACCOY.

Upon application we will send to any physician, who will pay expressage, a case containing an 8-ounce sample of this preparation.

THE MALTINE MANUFACTURING CO.,

19 Warren Street, New York.

THE BEST PREPARATION OF COD-LIVER OIL.

Of the very many flattering testimonials of the value of

GASWELL, MASSEY & GO.'S

EMULSION OF COD-LIVER OIL

With PEPSINE and QUININE,

none has afforded the firm more pleasure than the following from Professor LOOMIS :

"19 West 34th Street, New York.

"I have used Caswell & Massey's Emulsion of Cod-Liver Oil with Pepsine and Quinine for the past nine years, and it has given me greater satisfaction than any other preparation of Cod-Liver Oil that I have used. I can most cheerfully recommend it to my professional brethren.

ALFRED L. LOOMIS, M.D.”

CASWELL, MASSEY & CO.,

CHEMISTS,

1121 Broadway & 578 Fifth Ave., New York, and Newport.

CONTENTS.

EDITORIAL:

Koch's Discovery...

ORIGINAL ARTICLES:

197

I. The Surgical Treatment of Tubercular Laryngitis. By D. Bryson Delavan, M.D...... 198
II. Rouge's Operation for the Removal of a Nasal Sequestrum. By Charles H. Knight, M.D., 201
PROCEEDINGS OF THE SECTION OF LARYNGOLOGY OF THE NEW YORK ACADEMY
OF MEDICINE.......

A Further Communication on a Cure for Tuberculosis. By Professor Robert Koch................
CURRENT LITERATURE:

.....

...

202

206

Substitute for the Nasal Douche and Kindred Procedures-Apsityria-Contagiousness of
Crupous Pneumonia-Sudden Death during Tracheotomy from Hyperplasia of the Thymus
Gland-Spiro-Therapy-The Diffusion of the Respiratory Murmur over the Abdomen-
Chorditis Tuberosa-Catarrhal Otitis Media-The Treatment of Tubercular Laryngitis...212-216

Doctor:

You now find that your consumptive patients, with lowered vitality and exhausted tissues, are
unable to bear the cold weather. With impaired appetite and weakened digestion, they cannot take
and assimilate sufficient food to create the normal bodily heat.

Hence you notice them instinctively seeking the sunny side of the street, or hovering over the
fire, shivering. They are now losing ground more rapidly than ever, on account of the devitalizing
effects of the cold. The fear expressed by their acquaintances, that "The poor fellow will never
see spring again," you find justified by the cough, the increased sputa and the rapid increase in the
pulmonary lesions.

The cold, which is a tonic to those in good health, proves permanently depressing to them,
because their tissues lack sufficient tone to produce the necessary reaction.

What are you to do? Give up the case, of those in moderate circumstances, and send the rich
ones to some warm, malarious climate?

No, Doctor; keep them with you, under your own watchful supervision.

Home comforts where they are will more than compensate for balmy air, with hotel incon-
veniences, in a strange land. Meet the accidents and emergencies of the case according to their
indications as they arise, but place the patients at once and permanently on McArthur's Syrup, con-
taining the Hypophosphites of lime and soda in their chemical purity. This will so build up all the
tissues and impart tone and elasticity to the entire system, that a new life will spring np in the
patient, with a power of resistance fully equal to the normal. This will be of permanent value, as
it is not produced by temporary irritant stimulation, but by supplying the tissues with new food and
adding cells faster than they are exhausted by the disease.

By so continuing you can keep them on the upward grade, while others are constantly losing,
and, although the progress may be slow, yet you will find that your perseverance will be amply
rewarded. Such a course means all the difference between the early death and the final recovery of
a patient whose life may be very valuable to the family, friends and society.

The promise is surely worth the effort, and in consideration of the number of successes recorded
from such treatment, you could hardly be justified in a continued neglect of its benefits.

A sample bottle will be sent free if you will enclose your professional card and agree to pay
express charges.

A valuable treatise, "The Curability and Treatment of Consumption," free.

MCARTHUR HYPOPHOSPHITE CO.,

BOSTON, MASS.

+ GARDNER'S +

SYRUP OF HYDRIODIC ACID.

(HYDROGEN IODIDE.)

INTRODUCED IN 1878.

This is the original preparation of Syrup of Hydriodic Acid, first brought to the attention of the medical world in 1878 by R. W. Gardthe use of which has established the reputation of Hydriodic Acid

as a remedy.

Numerous imitations, prepared in a different manner, and not of the same strength, and from which the same therapeutic effects cannot be obtained, are sold and substituted where this Syrup is ordered.

Physicians are cautioned against this fraud.

The seventh edition of Gardner's pamphlet, issued in October, 1889, containing seventy pages of matter devoted to this preparation, its origin, chemical characteristics, indications, doses and details of treatment, will be forwarded to any physician upon application free of charge.

GARDNER'S CHEMICALLY PURE

SYRUPS OF HYPOPHOSPHITES.

Embracing the separate Syrups of Lime, of Soda, of Potassa, of Manganese, and an Elixir of the Quinia Salt; enabling Physicians to accurately follow Dr. Churchill's methods, by which thousands of authenticated cases of Phthisis have been cured. The only salts, however, used by Dr. Churchill in Phthisis, are those of Lime, of Soda and of Quinia, and always separately, according to indications, never combined.

The reason for the use of single Salts is because of antagonistic action of the different bases, injurious and pathological action of Iron, Potassa, Manganese, etc., in this disease.

These facts have been demonstrated by thirty years' clinical experience in the treatment of this disease exclusively, by Dr. Churchill, who was the first to apply these remedies in medical practice. Modified doses are also required in this disease; seven grains during twenty-four hours being the maximum dose in cases of Phthisis, because of increased susceptibility of the patient to their action, the danger of producing toxic symptoms (as hæmorrhage, rapid softening of tubercular deposit, etc.), and the necessity that time be allowed the various functions to recuperate, simultaneously, over-stimulation, by pushing the remedy, resulting in crises and disaster.

A pamphlet of sixty-four pages, devoted to a full explanation of these details and others, such as contra-indicated remedies, indications for the use of each hypophosphite, reasons for the use of absolutely ure Salts, protected in Syrup from oxidation, etc., mailed to Physicians without charge upon application to

R. W. GARDNER, 158 William Street, New York City.

W. H. SCHIEFFELIN & CO., New York, Sole Wholesale Agents.

OF THE

RESPIRATORY ORGANS.

VOL. II.

EDITOR:

NOVEMBER, 1890.

H. HOLBROOK CURTIS, M. D.

COLLABORATORS:

DR. JOSEPH O'DWYER, New York.
DR. ROBERT C. MYLES, New York.
Dr. S. O. VANDERPOEL, New York City.
Dr. ANDREW H. SMITH, New York City.
Dr. F. DONALDSON, Berlin, Germany.
Dr. VINCENT Y. BOWDITCH, Boston.
Dr. FRANKLIN H. HOOPER, Boston.
Dr. J. SOLIS COHEN, Philadelphia.
Dr. WILLIAM H. DALY, Pittsburgh.

Dr. E. FLETCHER INGALS, Chicago.
Dr. MOREAU R. BROWN, Chicago

Dr. F. WHITehill HinkeL, Buffalo.

Dr. W. H. GEDDINGS, Aiken, South Carolina,

DR. JOHN O. ROE, Rochester.

DR. WILLIAM PORTER, St. Louis.

Sir MORELL MACKENZIE, M. D. Lond. London, England.
Dr. PROSSER JAMES, London, England.

E. CRESSWELL Baber, M. B. Lond. Brighton, England.
Dr. G. HUNTER MACKENZIE, Edinburgh, Scotland.
Dr. GEORGE W. MAJOR, Montreal, Canada.
Dr. J. GOTTSTEIN, Breslau, Germany.

Dr. J. MICHEL, Hamburg, Germany.

Prof. F. MASSEI, Naples, Italy.

ARTHUR HILL HASSALL, M. D. Lond. San Remo, Italy. Dr. HOLGER MYGIND, Copenhagen, Denmark.

Contributions are invited from all parts of the world, whether subscribers or not.

All exchanges, books for review, and communications pertaining to the Editorial department should be addressed to Dr. H. Holbrook Curtis, 118 Madison Avenue, New York.

All letters relating to advertising, subscriptions, reprints, or other business, should be addressed to the Journal Publishing Company, 95 William Street.

Subscriptions from Foreign Countries, $1.50. The Editor does not hold himself responsible for opinions expressed by contributors.

EDITORIAL.

Koch's Discovery.

WE would call the attention of our readers to the recent communication of Prof. Koch, which is published in this number of the JOURNAL.

The author states that it was his original intention to defer any published account of his researches, until he was able by accumulated experience to give a complete description of his remedy and the method of its application. This, however, he found to be impracticable owing to the grossly exaggerated and false statements which

No. 11.

have been published, both regarding his methods and results. With a view to correcting these impressions, therefore, he consented to furnish this preliminary report.

In his paper, Prof. Koch does not throw any light upon the origin and preparation of the remedy; this, together with a statement regarding the theory of its action, he reserves for a future communication. He gives, however, a very careful account of his method of administering the remedy, and the remarkable effects which are produced.

In the author's opinion the application of the treatment results in a necrosis of the tissues containing the bacilli, and not, as has been supposed, in a death of the microorganisms themselves. This he has been able to learn by careful observation of the phenomena which occur in cases of lupus which have been subjected to this treat

ment.

After speaking of the general reaction which occurs in tuberculous subjects after an injection of the lymph, he states that a few hours later, the lupus begins to swell and to redden, this it does generally before the initial rigor. During the fever, the swelling and redness increase, and may reach so high a degree, that the lupus tissue becomes brownish and necrotic in places where the growth is sharply defined. We sometimes find a much swollen and brownish spot surrounded by a white area almost one centimetre wide, which is again surrounded by a broad band of bright red. After the disappearance of the fever, the swelling subsides, the necrotic tissue separates, and a crust is formed. This separates after two or three weeks, leaving a clean red cicatrix.

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