Personalized Anaesthesia: Targeting Physiological Systems for Optimal EffectPersonalized Anaesthesia presents a modern vision of anaesthesia. Integrating technology and knowledge from leading experts in the field, this book will change the way anaesthesia is both taught and practiced. Modern practice requires the anaesthetist to provide patient-specific management. This is the first resource to be organised by the desired physiological effect, rather than by drug groupings, explaining how physiological changes can be produced and controlled according to the characteristics of each patient and the particular surgical context. The book integrates physiology, pharmacology and technology, and applies these concepts in a systematic manner to each homeostatic system. This will optimise drug titration, effect quantification and decision making in anaesthesia practice to match the needs of the individual patient. Complex mathematical and scientific concepts are explained using accessible text, colour illustrations throughout and graphs. This is an essential text for any consultant or trainee working in anaesthesia. |
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Personalized Anaesthesia: Targeting Physiological Systems for Optimal Effect Pedro L. Gambús,Jan F. A. Hendrickx No preview available - 2020 |
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achieve activity acute administration agents allow alveoli anaesthesia anaesthetic analgesia analysis Anesthesiology approach arterial assessment associated autoregulation blood flow blood pressure body brain capnography cardiac output cause central cerebral changes clearance clinical cognitive combined compartment components concentration considered continuous core curve decrease defined depends depression described dose drug effect estimated example factors fluid frequency function haemodynamic hepatic human important increase indicates individual induced infusion injury interaction intraoperative limit liver loss lower lung maintain mean measure mechanisms method minutes monitoring muscle needed neuromuscular block normal occurs opioids optimal oxygen pain parameters patients performance perioperative pharmacokinetics plasma postoperative predict pressure prevent procedure propofol range reduced remifentanil renal respiratory response risk sedation signal stimulation surgery surgical temperature tion tissue values variability ventilation ventilatory volume