The Trustees of the Bender Hygienic Laboratory beg to call attention to the fact that this institution is now open and has been furnished by the Faculty of the Albany Medical College with all the most modern appliances necessary for the examination of pathological specimens, sputum, urine, water, et cetera. The various substances named are received under the following conditions: Pathological Specimens. Under this head come specimens relating to either human or animal pathology. Organs removed at autopsy, and whole tumors will be examined and reported on free of cost, provided that the same be accompanied by a clinical history of the case, and that the director of the Laboratory has the right to publish such cases either under his own name, or that of any one of his assistants or laboratory workers. For the examination of portions of tumors, or uterine scrapings removed for purposes of diagnosis, a charge of $5 00 will be made. It is desirable that whole organs, or tumors, should be received before having been submitted to extensive manipulation or the action of hardening fluids. Where such specimens can be transmitted within 24 hours of removal, they may be preserved by wrapping them in damp antiseptic gauze surrounded by oiled paper or rubber protective. In the case of small pieces of tumor, or uterine scrapings, the tissue should be placed in alcohol (50% to 957) or formalin (4% to 10%). Sputum. Sputum should be sent to the Laboratory in clean, wide-mouthed bottles. The ordinary vaseline bottle answers the purpose very well. A charge of $5.00 per examination will be made. Urine. A Urine should be in clean bottles in quantities of not less than six ounces. charge of $5.00 per examination will be made. The examination will be thorough, both chemically and microscopically. Water. As certain precautions are necessary in the examination of water, communications concerning this may be sent to the Director of the Laboratory, and special instructions will be forwarded to suit the individual case. Autopsies. The Director holds himself in readiness to perform autopsies outside of the city at the rate of $5.00 per hour of the time consumed. Letters and specimens may be addressed to Dr. GEORGE BLUMER, Director Bender Hygienic Laboratory, OFFICE HOURS, 9 to 11 A. M. Some one has said that "Iron and Manganese are like man and wife in physiological chemistry." Both are oxygen and hæmoglobin carriers. When combined in an organic, neutral and immediately absorbable form as in "Pepto-Mangan ("Gude") each aids the other in causing an increase in the number of red corpuscles and the amount of hæmoglobin which they contain. PEPTO MANGAN "GUDE" is ready for quick absorption and rapid infusion into the circulating fluid and is consequently of marked and certain value in all forms of Anæmia, Chlorosis, Bright's Disease, Rachitis, Neurasthenia, Etc. To assure proper filling of prescriptions, order Pepto-Mangan "Gude" in Samples and literature upon application to Laboratory, Leipzig, Germany. M. J. BREITENBACH COMPANY, AGENTS FOR AMERICAN CONTINENT, 100 WARREN ST., (Tarrant Building,) NEW YORK. of the Medical Profession is directed to this remarkable Curative Preparation, as it has been endorsed by THOUSANDS OF THE LEADING PHYSICIANS OF THE UNITED STATES, who are using it in their daily practice. COLDEN'S LIQUID BEEF TONIC is invaluable in all forms of Wasting Diseases and in cases of convalescence from severe illness. It can also be depended upon with positive certainty of success for the cure of Nervous Weakness, Malarial Fever, Incipient Consumption, General Debility, etc. COLDEN'S LIQUID BEEF TONIC Is a reliable Food Medicine; rapidly finds its way into the circulation; arrests Decomposition of the Vital Tissues, and is agreeable to the most delicate stomach. To the physician, it is of incalculable value, as it gives the patient assurance of return to perfect health. Sold by Druggists generally. The CHARLES N. CRITTENTON CO., General Agents, Nos. 115 and 117 Fulton Street, NEW YORK. HYDROZONE (30 volumes preserved aqueous solution of H2O, IS THE MOST POWERFUL ANTISEPTIC AND PUS DESTROYER. GLYCOZONE (C. P. Glycerine combined with Ozone) IS THE MOST POWERFUL HEALING AGENT KNOWN. Successfully used in the treatment of Gastric and Intestinal Disorders (chronic or acute) "Half an hour before meals, administer from 4 to 8 ozs. of a mixture containing 2 per cent. of Hydrozone in water. Follow after eating with Glycozone in one or two teaspoonful doses well diluted in a wineglassful of water." Send for free 240-page book "Treatment of Diseases caused by Germs," containing reprints of 120 scientific articles by leading contributors to medical literaturc. Physicians remitting 50 cents will receive one complimentary sample of each, "Hydrozone" and "Glycozone" by express, charges prepaid. Hydrozone is put up only in extra small, small, medium and large size bottles bearing a red label, white letters, gold and blue border with my signature. Glycozone is put up only in 4-oz., 8-oz. and 16-oz. bottles bearing a yellow label, white and black letters, red and blue border with my signature. Marchand's Eye Balsam cures all inflammatory and contagious diseases of the eyes. Charles Marchand, Sold by leading Druggists. PREPARED ONLY BY Charles Marchand Chemist and Graduate of the "Ecole Centrale des Arts et Manufactures de Paris" (France, 28 Prince St., New York. Avoid imitations. Mention this Publication ALBANY MEDICAL ANNALS For the ANNALS. Original Communications. SOME NOTES ABOUT THE CITY OF OSAKA, JAPAN; ITS SANITATION, HOSPITALS, PRACTITIONERS AND DISEASES. BY HENRY LANING, M. D., Medical Missionary (American Episcopal Mission), in Charge of St. Barnabas' Hospital, Osaka; Honorary Secretary, Osaka Municipal Council. The city of Osaka is situated on the banks of the Yodo river, near its entrance into Osaka bay, at the head of the inland sea. Next to the capital the largest city in the empire, it is the commercial metropolis and chief manufacturing town. The river being navigable only to coasting steamers and other vessels of light draught, it has been dependent upon the port at Kobe, twenty miles distant, for foreign shipping facilities; but a harbor. at the mouth of the river which will be accessible to ocean-going steamers is now in course of construction — to be completed in eight years at a cost of over 21,000,000 yen which will make this a principal shipping port; and its location having natural. advantages of defense, it being a chief railway center and military rendezvous, it may become also a first-class naval basis. Along the eastern confines of the city is a plateau, on which is situated what was once the strongest fortress in the empire the Osaka Castle which was built in the seventeenth century, when the city was the military capital, and which was the last stronghold of the Tycoon to surrender to the imperial forces at the time of the restoration of the Emperor to power, in 1868. Here are now located extensive military barracks and parade grounds. Near by is the arsenal, and on the opposite bank of the river the imperial mint. Aside from this slightly elevated ridge, the land upon which the city is built is low and flat, and so intersected by natural and artificial - that the place has been There is little else, how water-courses styled by some the Venice of the East. ever, to sustain the comparison. The rivers and canals are crossed by about three hundred bridges, and over sixteen thousand jinrikisha ply the numerous streets at full man-power speed. Freight carts are drawn by coolies, and wheelmen and men on horseback, with betto ahead to clear the way, are occasionally seen. Most of the streets are too narrow to admit of horse-carriage driving. They are swept daily, and in dry weather frequently watered. They are the playground for young children, and some are thronged with pedestrians, but collisions resulting in injuries requiring surgical aid are rare. The town is compactly built over an area of eight square miles. It is lighted by electricity and has telephonic accommodations. On account of greater difficulties to be overcome, it is behind some other Japanese cities in the introduction of electric tramways. The buildings are tile-roofed, and, excepting the public buildings, temples, manufactories, warehouses and an increasing number of office buildings and stores in foreign style, the houses are mostly unpainted wood-and-plaster structures of one-and-a-half stories, adjoined to each other at the sides, and with a miniature landscape garden in the rear or in a court. There is one public park, a small one recently laid out, and there are places of open-air resort in the suburbs, but the rivers afford the chief breathing space, and in summer are largely resorted to in pleasure boats. Clear, bright weather prevails as a rule during most of the year, though the air is sometimes laden with smoke from more than a thousand smoke-stacks of the cotton-spinning mills and other manufacturing establishments which have been started during the last few years. In winter the temperature seldom reaches freezing point, but the humid atmosphere and cold winds from snow-capped mountains necessitate the wearing of heavy clothing. The annual rainfall averages about fifty inches. There is usually a rainy season in the early summer, followed by continuously hot weather till the middle of September. The |