ments of a class in which opiates are indicated, but in which the 'remedy is worse than the disease.' One case in particular has given me a great deal of trouble for years. I have tried opium in every form, and many other narcotics, alone and in combination; but constipation, nausea and nervous prostration have been the inevitable results. Some two months since I obtained some papine and commenced on this case, with the happiest effect."

SCOTT & BOWNE, manufacturing chemists of New York, make a specialty of producing an emulsion of cod-liver oil with hypophosphites. Their great care in selecting the oil and in making the combination is amply proven by the high therapeutical value set upon the emulsion by the profession. It is no new remedy, but has been steadily growing in demand for a number of years. It is certainly very useful in restoring wasting tissue, and in cases of scrofulous children it acts almost as a specific. They also offer a buckthorn cordial which is highly useful in the treatment of constipation.-Massachusetts Eclectic Medical Journal.

HYPODERMIC USE OF LISTERINE.-There is one mode of its administration to which attention may be called. I allude to its hypodermic administration. Keeping in view the fact that it is antiseptic, tonic, non-toxic, its use is indicated in cases of too rapid retrograde metamorphosis, or perversion of vital force. During the past four years I have proved this to my entire satisfaction. For the past four months this section has been scourged with a severe epidemic of dysentery and cholera infantum. I have used listerine, when indicated, by the mouth, by rectal injection, and hypodermically, and the latter method has always yielded the best results.-F. A. Rew, M. D., in Medical Bulletin.

Two CASES OF DYSMENORRHEA.-(1) Young married woman with extreme dysmenorrhoea. Examination revealed a lacerated cervix (this trouble was consequent to parturition), and an aggravated endometritis. Treatment was given for one month, consisting of local applications and in the internal administration of aletris cordial. Patient positively cured, much to my surprise, as my prognosis was far different. (2) Girl, fifteen years of age. Commenced to menstruate at fourteen. For nine months previous to treatment had not been free from pain in lumbar region. A scanty, coffee-colored flow, attended with intense pain, at irregular intervals. Cephalalgia, nausea and constipation, superadded, had rendered her peevish, melancholy,

and anæmic. Administered one bottle of aletris cordial, teaspoonful doses, quieted pain with suitable analgesics, and in two months discontinued all treatment. Heard from her as follows: Had menstruated once with scarcely any pain, the color was normal, her lumbar distress had disappeared, and color was returning to her cheeks. Can highly recommend the aletris cordial, and shall expect great results myself.-H. S. Drake, M. D., Middleboro, Massachusetts.

It is a well known fact that there are druggists in every large city who are not to be trusted with the filling of a prescription that calls for any expensive drug. They come and go, so that at last physicians are compelled to designate certain of the drug fraternity as trustworthy, and insist upon their patients going to these alone for their medical supplies. If they fail to do this, their work is thrown away and their reputations go with the failure of their remedies in critical cases. A few cases from actual observation and experience will illustrate this better than a volume of argument. (1) Thirty grains of quinine, in three doses, to be taken at hourly intervals, were prescribed for a young man suffering from ordinary intermittent fever. The doses were taken as directed, but no signs of cinchonism were induced, and the disease progressed without change. The same doses, in "Warner's sugar-coated pills" were ordered, with the effect of inducing well marked cinchonism with cure of the disease. (2) In a case of profuse menorrhagia, one ounce of fluid extract of ergot was ordered, with directions to take one fluid drachm every hour until the hæmorrhage ceased. The entire amount was taken without result. An ounce of "Squibb's fluid extract of ergot" was ordered-same directions, and the flooding ceased after the second dose. (3) Four ounces of a mixture of bromide of potassium and chloral, each an ounce, with tincture of hyoscyamus and fluid extract of cannabis indica, in appropriate doses, were ordered, with directions to take one teaspoonful every hour until sleep should be induced. An ugly, muddy mixture was received, which produced nausea and headache, but no sleep. A similar prescription instead of the above extemporaneous officinal combination, was ordered only "Battle's bromidia" was designated, which induced refreshing sleep after a few doses of from twenty to thirty drops had been taken.Extract from an article in the December Medical Brief, by William B. Hazard, Professor of Principles and Practice of Medicine, College of Physicians and Surgeons, Saint Louis.

BY HENRY O. MARCY, A. M., M. D., BOSTON, MASSACHUSETTS.

The present paper is a further contribution to the study of perineal injuries, and is evoked in part because of an interesting article, published in the Obstetric Gazette for March, by Dr. J. M. Baldy, of Philadelphia. From previous contributions upon this subject, my opinion and methods are well known to the profession and my present observations are based upon the studies made of over fifty operative cases since my last article, published in the "Transactions of the International Medical Congress of 1884." I cannot but express surprise that the anatomy and function of the perineum seems so little understood by the profession at large and, when we consider that the general practitioner must meet with conditions where the floor of the pelvis may be endangered in every case of labor, it seems strange that so little attention and thought are given to the subject. Suffering, dependent upon injury, is the daily complaint, and nervous disturbances, in great variety, result therefrom. Such cases are common even when there is no prolapse and where the restoration of the parts is followed by permanent relief.

The parturient and fecal canals are supported in the pelvic basin in close apposition and the functional relationship is often such that the one may encroach upon the other in such a way as to occupy nearly all the space accorded to both. This is especially