Guy's Hospital Reports

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Page 390 - The prize is open- for competition to the whole world, but the essay must be the production of a single person. The essay, which must be written in the English language, or if in a foreign language, accompanied by an English translation, must be sent to the College of Physicians of Philadelphia, Pennsylvania, USA, before January 1, 1898, addressed to Barton Cooke Hirst, MD, Chairman of the William F.
Page 390 - Each essay must be accompanied by a sealed envelope containing the name and address of the author and bearing on the outside the motto or device which is inscribed upon the essay.
Page 99 - ... dry and shrivelled skin and extreme emaciation usually attendant on protracted malignant disease; slight pain or uneasiness is from time to time referred to the region of the stomach, and there is occasionally actual vomiting, which in one instance was both urgent and distressing; and it is by no means uncommon for the patient to manifest indications of disturbed cerebral circulation.
Page 99 - The patient in most of the cases I have seen has been observed gradually to fall off in general health; he becomes languid and weak, indisposed to either bodily or mental exertion ; the appetite is impaired or entirely lost ; the whites of the eyes become pearly ; the pulse small and feeble, or perhaps somewhat large, but excessively soft and compressible ; the body wastes, without, however, presenting the dry and shrivelled skin and extreme emaciation usually attendant...
Page 99 - For a long period I had from time to time met with a very remarkable form of general anemia occurring without any discoverable cause whatever — cases in which there had been no previous loss of blood, no exhausting diarrhea, no chlorosis, no purpura, no renal splenic miasmatic, glandular, strumous, or malignant disease.
Page 157 - And the priest shall look on the plague in the skin of the flesh : and when the hair in the plague is turned white, and the plague in sight be deeper than the skin of his flesh, it is a plague of leprosy : and the priest shall look on him, and pronounce him unclean.
Page 99 - I, perhaps with little propriety, applied to it the term "idiopathic," to distinguish it from cases in which there existed more or less evidence of some of the usual causes or concomitants of the anaemic state.
Page 99 - The leading and characteristic features of the morbid state to which I would direct attention are, anaemia, general languor and debility, remarkable feebleness of the heart's action, irritability of the stomach, and a peculiar change of colour in the skin, occurring in connection with a diseased condition of the
Page 100 - This discoloration pervades the whole surface of the body, but is commonly most strongly manifested on the face, neck, superior extremities, penis, and scrotum, and in the flexures of the axillae and around the navel. It may be said to present a dingy or smoky appearance, or various tints or shades of deep amber or chestnut-brown; and in one instance the skin was so universally and so deeply darkened that but for the features the patient might have been mistaken for a mulatto.
Page 100 - ... or less manifestation of the symptoms already enumerated, we discover a most remarkable, and, so far as I know, characteristic discoloration taking place in the skin, — sufficiently marked indeed as generally to have attracted the attention of the patient himself, or of the patient's friends.

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