child to the nurse, as, though we are morally convinced that the ulcer of the nipple was of specific character, it was not accompanied by other symptoms which would give that undeniable evidence that science requires.

The question here at issue is, through which channel has this child been infected?

The most thorough ocular inspection of the mother only proved her to be a very healthy woman, devoid of any specific taint; neither can we consider, as already implied, the nurse to be the cause of infection. On questioning the mother of the child closely if her husband had had any disease, we hear that he was suffering for a long time, more than a year ago, from sore throat and ulcers on the tongue, so that for some time he was not able to take solid food, from the pain caused by its contact with the tongue. have not yet been able to see her husband; but as no other way of infection could be detected, this more than suspicious sore throat, with ulcers on the tongue, may well be considered as the cause of the secondary syphilitic symptoms in the child, directly transmitted in generation by the father.

I

But it will be objected, the throat affection of the father was not syphilitic, else how was it possible that in this case secondary syphilis could be communicated to the offspring without the mother being infected? is it at all likely that a wife can escape scatheless from cohabitation with a husband infected, as we consider this one to have been? It cannot be denied that in most cases the father is rarely affected with syphilis without communicating it to the mother, either before or during pregnancy, so as to render it often difficult to decide from which of the parents a syphilitic child has inherited the disease. This circumstance has led some writers to the erroneous conclusion that the power of the father to transmit syphilis to his child is much more limited than that of the mother; some even deny it altogether (Vassal, Bouchet). However, numerous conclusive facts confirm, beyond any doubt, the theory that syphilis can be transmitted from father to child without infecting the mother. Cedersehjold, Swediaur, Bertin, Depaul, Baehr, and others, quote cases in support of this

view, which stand the test of criticism.

If our case is not as conclusive in its evidence, it contributes at least morally to corroborate the possibility of the direct transmission of syphilis from father to child.

ON THE RELATION OF PERUVIAN BARK (CORT. CHINE) TO INTERMITTENT FEVER.

By Dr. LANGHEINZ, of Darmstadt.

(Continued from page 232.)

THERE certainly remains, even then, the bare supposition that all the symptoms originate from a single prover, which I hold to be at least probable; so here also there is a lack of information as to the experimenters and the size of the doses. In spite of these defects, we may be allowed to make the attempt with the symptoms of, 1st, Wislicenus; 2nd, Hartmann; 3rd, Meyer; and, 4th, Wagner.

The results of the proving of Wislicenus are arranged chronologically as follows:

We may conclude from symptom 585, that early in the morning he took a dose of (tinct.?) Chin., and probably a considerable one.

In a quarter of an hour, symptom 415-Pricking like needles over the right shoulder-blade, and on the left side of the chest.

In half an hour, symptom 83-A momentary contraction in the forehead, as if it drew the skin to a central point.

In an hour, symptom 394-Periodical dull stitches in the cavity of the chest from within outwards, whether at rest or moving, and without regard to respiration.

In two hours, symptoms 343 and 344-Increased discharge of urine with burning in the orifice of the urethra, continued burning there, with a sensation of soreness on the

edge of the prepuce; both especially painful from the friction of the clothes.

In three hours, symptom 85-Pressure on the face, especially near the nose and cheek, with contraction of the eyelids, as if the upper and lower were drawn towards each other.

In four hours, symptom 627-Internal chill without perceptible external cold.

In six hours, symptom 103-The left lower eyelid twitching hither and thither.

In sixteen hours, symptom 585-In the evening, on falling asleep, awakened by confused dreaming visions.

In twenty-one hours (i. e., not very long after midnight?), symptom 421-Painful wrench in the sacrum.

In twenty-four hours (early on the second day) symptom 378-Pressure outwards in the region of the lowest rib (right or left?).

In forty-eight hours (early on the third day), symptom 316-Abundant discharge of flatus, with a drawing-in the abdomen during a hard, difficult stool.

In seventy-two hours (early on the fourth day), symptom 474-Tearing in the thigh bones from above downwards, both at rest and when moving, by fits, for several days (consequently, no doubt, on the fifth day, of which no notice was taken).

After six days (on the seventh?), symptom 122-Pain on the left ear, on touching it.

After eight days (on the ninth ?), symptom 154-Scraping on the palate, even without swallowing; and symptom 477 -Painful sensibility of the skin on the thighs from the friction of the clothes, as if the skin were raw and covered with pimples.

After nine days, symptom 8-Confusion of the head like a cold (from the China taken ten days previously?); and symptom 354-Cold in the head, with sensitiveness of the nose, and a few pimples, sore to the touch, on the edge of the nostrils and the septum nasi. (Evidently an independent

affection which has nothing to do with China).

Lastly, after eleven days, symptom 202-A feeling of emp

tiness in the gullet and oesophagus (what is the distinction between "gullet" and "oesophagus ?") With symptoms 127 and 596 no time of occurrence is added.

On a review of all this, there is (as the gentle reader will say to himself) only need of the very simple remark, that we have not before us the slightest indication of a typical process, or of an intermittent fever.

We subjoin the chronological review of the results of a proving by F. Hartmann, consisting of thirty-eight symptoms.

This work of Hartmann's seems to be decidedly the best of all that we have as yet found in the Materia Medica Pura; it seems likewise highly probable that Hartmann himself was the prover. From symptom 219, one may infer that the time of taking the medicine was the forenoon. The quantity is unfortunately not known.

The sequence of symptoms then is as follows:

Immediately after taking it, a bitter taste in the throat, obliging him to be constantly swallowing saliva (175) and eructate (204). In a quarter of an hour, pupils much dilated (110), yawning, and stretching of the limbs (597). In half an hour, a contraction in the scrob. cordis impeding the respiration (237). In three-quarters of an hour, pupils contracted (107), and with that the pulse slower and weaker, but gradually becoming quicker and stronger (686). In one hour, shuddering all over, with goose skin (623), and rigor universally, with icy cold hands and no thirst (633). This state either continued for two hours, or else, after a shorter duration, returned in two hours; the report of "one to three hours" unfortunately not being distinct.

In an hour and a half, the following group of symptoms were developed :

Dilated pupils (109); pinching stitches in the left hypogaster (254); pulse slower and more languid (685). Further, in two hours and a half, minute fine pricking pains in the upper molars on the right when touched; drawing in fresh air neither relieves nor aggravates. In three hours, as above, universal rigor with icy cold hands and no thirst (633). Further, in four hours, continued shooting

in the region of the liver, neither diminished nor increased by inspiration or respiration (256); at the same time, tightness of the chest, with difficult and sometimes rattling expiration (especially when walking), and rawness of the chest (368). In four hours and a half, universal heat, with swollen veins on arms and hands, but neither perspiration nor thirst (671). In five hours, jerking drawing in the upper back molars on the left side (142): at the same time, violent stitches from within outwards in the region of the liver, only on expiration (257), and little stitches on the middle of the spine (416). In five hours and a half, cramp-like paralytic pain in the right thigh and knee-joint, on rising from a seat after sitting for some time, and on walking (481). In six hours, contractive pinching pain on the outer side of right foot, on the side of the sole (504). In eight hours, painful pressure and squeezing in the head towards the forehead, as if everything in it were too heavy and were going to be squeezed out; relieved by strong pressure of the hand (31). In eight hours and a half, a pressing, fine stitch on the left side of the chest (386). In nine hours, drawing, tearing pain in the left shoulder-blade (413), and, at the same time, pressing, squeezing pain in the head, aggravated by fresh air (29). In nine hours and a quarter, pain in the head, a boring in the left side of the head when sitting (32). In nine hours and a half, very severe thirst, and thereupon burning heat all over, with throbbing in all the veins; no sweat nor thirst; violent burning in the ears and forehead, whilst the cheeks, hands, and feet are but ordinarily warm, and yet those parts feel too hot inwardly. This seems (663) to have continued till after ten hours and a half, and was then synchronous with painless pressure in the eyes, as if from weariness and want of sleep (99), which returned in an hour and a half (i. e., after twelve hours in all), and, moreover, with (653) greatly increased heat in the whole of the face, the trunk and thighs, with cold sweat on the forehead, cold cheeks and feet. This, however, is not to be identified with symptom 663: one must then suppose that one symptom or the other is given inaccurately, or else a misprint must have crept into the report of the time.