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7. The treatment of tetanus consists in lapping cloths saturated with the tincture round the jaws and head of the patient, and in giving three spoonfuls of the same preparation or of the pure juice, repeating the dose as is done with opium in like cases. In spasm of the stomach, give four spoonfuls of the juice, or, better still, of the tincture, and apply the above mentioned cloths to the region of the stomach.

8. In " la etica," i. e., hectic fever, consumption, give an infusion of the leaves, made with hot water.

9. For asthma, use the same measures as are described in the fifth paragraph.

10. In tertians and all fevers with chills, four spoonfuls of the tincture or of the pure juice should be administered at the beginning of the rigor, and continued in equal doses, fasting, for a month.

11. The author of the memoir from which some of these remarks are drawn does not say how Guaco is to be employed as a vermifuge. In my opinion we should give the pure juice, or the tincture, in doses of one spoonful for children and two for adults, fasting.

12. In order to cure hemicrania radically it is necessary to give fasting two spoonfuls of the juice, or of the tincture, and as much more a little before meals.

13. For toothache, some of the juice or the tincture should be rinsed in the mouth, and applied on cotton to the painful part.

Cases.Guaco has proved successful in so many different diseases, that if every case were referred to it would be necessary to write a treatise; hence, I shall here confine myself to the most remarkable of those which the aforesaid memoir contains, and to few of the many which have come under my own more immediate notice.

1. In 1828, a servant of the Sras Martinez was bitten in the hand by a coral snake. The tincture was given and within eight days she was perfectly well. The same remedy cured, in 1830, a servant of General Juan de Escalona. She was bitten in the finger by a snake of unknown species, and was under treatment for three days. Sr. Antonio Eodriguez, who had caused himself to be inoculated with Guaco, was on such familiar terms with the most venomous snakes, that he had always some of them in his house, in his clothes trunk, and even in his bed. On one occasion he carried a rattlesnake in the crown of his hat, and some friends to whom he showed it having irritated it, it bit him in the head when the hat was put on, but without the least bad result. Inoculated persons acquire a certain power over snakes, as is proved by what frequently took place in the district of Argua where two boys who had been inoculated by Seiior Benitez used to go out into the fields, catch snakes, and return playing with them.

2. The author of the memoir does not mention any instances of the bite of the alecran, nor has anything reached me through other channels.

3. According to the statement of the late Dr. Cristobal Mendoza, Governor of Venezuela, four negroes were bitten by a rabid dog. Three of them were treated by the usual remedies and died of hydrophobia; the fourth was treated with Quaco and escaped. Sefiora Porte, sister-in-law to General Juan de Escalono, and her servant were bitten by a rabid dog. Both at once took daily three spoonfuls of pure Quaco juice, applying it also to the wounds, and continued this for forty days. They did not fall victims to this terrible disease. Sr. Pedro Alcala was bitten in the arm by a mad dog and escaped by virtue oi Quaco treatment. It must be noted that two of the dogs just mentioned bit various animals all of which died rabid. Last year and this hydrophobia has been very rife amongst dogs in the whole province, and Quaco has been increasingly employed with the best results. I have been assured that for this reason the English Consul has written to London some interesting accounts of the virtues of this plant.

4. A woman, named Serafnia, suffered from rheumatism for ten years, and became crippled by it. She then took Guaco, which restored her health and the use of her limbs, and I have seen her walking along the street without difficulty. A trustworthy person informed the author of the memoir that a foreigner whom the gout had crippled was so thoroughly cured by Quaco that shortly after his recovery he made a journey on foot from this city to Guavia, and that the complaint did not return.

5. A child of Carlos Mendoza fell from the second story of the house into the court below and was badly injured in the face and all over the body. Cataplasms of the leaves were applied to the wounds and contusions, and the pure juice was given internally, with success.

6. Sras Martinez, who has heen already referred to, had a slave suffering from arrest of the catamenia. A complete cure was effected by the treatment mentioned above in the fifth paragraph.

7. The late D. Francisco Espejo relates that a disease of the liver, which had afflicted him for a long time, having brought him into a desperate condition in the judgment of his physicians, a negro cured him with drinks of Guaco juice and cataplasms of the leaves put over the liver. A slave attacked with the same disease was given up by her physician, who said she could not survive five days more. Guaco was employed as in the previous case and succeeded in restoring her health so completely and so quickly that at the end of a month she returned to work and laboured on a par with the other slave.

8. Seiior Pedro Edwards cured one of his slaves who had suffered for four years from a scrofulous ulcer in the neck, by giving the juice and applying cataplasms of the leaves.

9. Col. Diezo Vallenilla states that in Cumana, his country, no one dies of tetanus and spasm of the stomach when Guaco is used according to the directions given in the seventh paragraph. I do not know if this remedy has been employed in our city in such cases, which are rarely met with.

10. A slave of Senor Feliciano Palacios had all the symptoms of consumption resulting from suspended menstruation, and was cured with an infusion of the leaves prescribed by an Indian.

11. A slave of Col. Francisco Abendano was afflicted with asthma and had a severe attack of rheumatism. Guaco was administered for the latter, and it cured both diseases. The wife of Dr. F. Javier Taney gave the tincture to a slave who was an asthmatic, and obtained the best results.

12. Senor Pedro Edwards, already cited, cured a Spaniard of a tertian fever contracted in the Antilles, by giving Guaco for a few days.

13. The author of the Memoir does not mention any specific cases of worms, but it is a fact that many persons who have resorted to Guaco for other reasons have destroyed these parasites.

14. Senor Eduardo, a frequent sufferer from violent hemicrania, got rid of it by taking Guaco tincture.

Hypodermic Injections of Filtered water to Relieve Pain.*

In the September number' of the Art Midical, Dr. Jousset reports cases treated by him at the Hopital St. Jacques." In three of these cases he made use of hypodermic injections of filtered water in the treatment of the symptom pain.

Case 1.—G. L—, aet. 37, stone-cutter, was admitted on January 11th, and discharged March 20th. He was suffering from pleuritis when admitted, and while in the hospital he got an attack of acute rheumatism.

Up to February 18th patient was treated with Aeon., Canth., Kali, Mang., Chin., Sul., Merc, sol., and on this day there was considerable amelioration, especially of the fever; the pulse had fallen to 84 since some days; at this stage we (Dr. Jousset) made some hypodermic injections of simple water; the pains diminished very perceptibly and the patient was at last able to sleep.

The pulse having fallen to 72, the pains having abated, the subcutaneous injections of filtered water having several times stopped attacks of pain, the Quinine was replaced by Ghin., 3 trit., this by Sulph. 12., and the pleuritic exudation being pretty well absorbed, the patient was discharged on March 20th at his own request.

Case 2.—M. T—, a man aet. 28, was admitted on February 11th, suffering from gouty arthritis confined to the right shoulder. The pain is very violent, the patient can make no use whatever of his arm, the joint is red, hot, and swelled.

On Saturday, January 15th, we made an injection of water simply filtered; twenty-five minutes thereafter the patient felt himself greatly relieved, and at night he got a little sleep.

On Sunday, the next day, we made another similar injection; after which the patient could readily move his arm, and he slept well the following night.

On Monday we made a third and last injection. Ever since the joint had been perfectly free, and, moreover, his sleep has been excellent. Hypodermic injections of filtered water exercise an incontestable action on the symptom pain, but here it is only right to mention that China, 3 trit., had already begun to effect improvement.

* From the Art Medical. Extracted by Dr. Burnett.

Case 3.—A woman suffering from intercostal neuralgia. She was subjected to subcutaneous injections of filtered water; these injections relieved her,* but one of them caused a subcutaneous abscess.

Dr. JoUsset concludes thus: "Let us for a moment recur to this question of the hypodermic injection of water as a means of combating the symptom pain. This method at first seemed to us so very paradoxical that we most unwillingly consented to try an experiment with it. The conclusions which we have been enabled to arrive at from a consideration of the three cases in which we triedthe experiment may be thus stated. Both in the rheumatic and in the gouty arthritis the pain was incontestably relieved after such injection. In the case of intercostal neuralgia the pain was not only not relieved, but the fourth or fifth injection resulted in an abscess of the size of a walnut. We have therefore the fact of the relief of the pain of arthritis by the injection of water, a fact which thus far appears inexplicable, "t

Homceopathy and " Scientific Medicine."

The following passage occurs in the Address delivered by Prof. Humphrey, of Cambridge, at the late annual meeting of the British Medical Association.

"The physiologically antagonistic influences of atropia and physostigma, and the fact that a poisonous dose of the one may be given with impunity if the other is administered along with

* There is a discrepancy with regard to the result of the injection in the case of the intercostal nenralgia. Thus, on p. 162, Dr. Jousset says, " Ces injectiones la soulagerent, S,c." i. e., these injections relieved her. But on p. 174 he says," Dans le cas de neVralgie intercostale ou ce moyen a 6te applique il a ete inefficace contre la douleur, &c.," i. e., in the case of intercostal neuralgia in which this means was adopted, it was inefficacious, &c.

t I think it is to be explained by the well-known action of pure water on protoplasm, upon which it acts as a strong stimulus, causing it to become contracted and finally to lose its irritability. According to J. Kanke, " distilled water acts as one of the most violent poisons to muscular and nervous substances" (Physiologie, p. 118). The cause is probably the great capacity for imbibition possessed by pure water. This acting in excess becomes a force first stimulating then destroying the very complex molecules of the living matter. This action of pure water seems not to have been hitherto sufliciently considered in the method of hypodermic injection.—J. Okysdale.

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