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barb, Ziv; gum guaiaci, 3j; nutmeg, No. j. Blood Examinations in East African MalaMisce. The patient took two tablespoonfuls in

rial Diseases. a small tumbler of hot wine and water when

BY E. GRAWITZ, Staff Physician at II Medical Clinic, Berlin. going to bed, and the same quantity before rising in the morning, remaining in bed until

[Review by Wm. Krauss, M.D., Memphis.] any perspiration that was occasioned had sub- This investigator has examined the blood of sided. The treatment was continued until a six officers who had done duty in the East Afriperceptibly good effect had ensued, when only can German Colonies. one teaspoonful was administered at a dose un Four of these cases had remained well and til the mixture was used up.-N. Y. Med. Jour without plasmodia since their return home some nal.

months since. In three there was still marked

diminution of red corpuscles at this time. In Infusion of Triticum Comp.

all six of the cases, as well as all of the domesThis term I would apply as a proper pro

tic cases of malaria examined, Grawitz finds fessional name to the advertised" Garfield Tea."

a marked increase of eosinophilous cells.* The This popular laxative and diuretic composed of fifth case was peculiar. This patient stood the

Southern climate well at first, but soon became the simplest herbs, as a proprietary medicine, makes these herbs altogether too expensive for

ensive for


the subject of short attacks of chills, with fever poor people. I therefore suggest the term above

and sweating, but at irregular intervals. At and present the formula for it as follows:

first he rallied well from these, but finally he

succumbed, presenting all the symptoms of R. Sennæ folii Tritici repens........................... då 25 parts.

our (Mississippi Valley) chronic malarias, viz., Balmoniæ.... ...........1 part.

chilly sensations, malarial pains, headaches, M. One to two heaping teaspoonfuls to a cup of water, steeped as common tea should be steeped, viz. : Put in tin dish and pour the water on absolutely boiling hot; stir and steep three minutes and no longer. This extracts the virtue and leaves the bad taste and

remission. He returned to Berlin, pale, withgriping elements of the senna bebind. Drink this as hot as out fever, enlarged spleen, no other changes. possible on retiring at night. There is no griping about it and ihe light stimulation of the kidneys is more agreeable than other- A few days later had slight attacks, was wise.

extremely weak, and complained of palpitaThis, taken in greater or less quantities every tion. Blood examination showed 4.5 million night for a time, will work wonders for those red, 16,000 white corpuscles, eosinophilous who need the laxative. As for the diuretic cells somewhat increased, and small roundish qualities, they are as much needed as were the

and ovoid, delicate, colorless bodies, within red diuretic qualities of the waters of a certain

blood corpuscles, without pigment, and showing spring near a girl's seminary. The seminary energetic voluntary motion. In a few days was advertised over the advantages the young longer irregular pigmented bodies, and still ladies might receive from these diuretic waters, larger, round, still more pigmented forms. as though all girls needed them.

taking up almost the entire red corpuscles, some Any apothecary can prepare and keep on of their contours extending even beyond its hand such mixtures of herbs, using better senna

margin. They were extremely few, often rethan that found in the proprietary Garfield quiring half a day to find a single one. Tea. This makes a very convenient mixture "As is well known these large pigmented for every family to keep on band for family forms are always precursors of an attack, but use, and offers a proper prescription for the this was not the case with this patient. Nor physician.-E. CHENERY, M.D., in Times and

were there any forms with flagellæ, but the Register.

next examination from this patient showed a

form entirely different from the forms of acute Phytolacca decandra (the common poke root malaria,t the semilunar plasmodium of Laveran. and poke berries) is acquiring a reputation as an "anti-fat,” or remedy for surplus flesh. . *White blood corpuscles, capable of taking on eosin stain, a

property discovered by Ehrlich, who believed them diagnostic of beginning leukemia.

For the benefit of those of the readers who have not kept up DOCTOR-Have you been wishing to adopt the con with the literature on malarial parasites, it might be well to give venient and most efficient alkaloidal or dosimetric

the author's review of the same. The Italian investigators have

done more in ihis line than all others, they having had more granules in your practice, but hesitated on account of

abundant material at their disposal for studying the varieties lack of definite knowledge as to how to use them ? and biological relations of this parasite, first discovered at The new book “Outline of Treatment with Dosimetric

scribed by Laveran, and later named plasmodiam malariæ by

Marchiafava and Celli. Granules” will meet your needs admirably. It is the Italian authors distinguished (see Memphis Journal Medical only book published treating this important subject Sciences, December, 1890.) three principal developmental series

characterized by their morphological character, arrangement, from the standpoint of the American practicing physi

presenee and absence of pigment, etc. can. It meets the difficulties that are encountered at In the beginning of a paroxysm all three varieties commence the bedside and in the consulting room. Bound in their cycle with the appearance of small roundish or ovoid bodies. flexible cloth, small pocket size, 106 pages, price only

which grow inside of the red blood disks, and at the expense or

their hemoglobin, as a rule forming pigment in their center, and 50 cents See order blank on page xxvi.

after many changes of form becoming larger, and giving ott spares

This parasite is still the subject of lively contro corpuscles to 20,000 on twenty-fifth day, about versies, Golgi believing it to be the plasmodium twenty to twenty-five per cent. being eosinophiof the current malarias, paroxysms coming on lous cells. The author concludes by calling at longer intervals. Others believe it to be char attention to the value of blood examinations acteristic of chronic malarias. They have before giving quinine. never been found except in malarias of the The observations given above coincide with Southern climate.

those of Dr. E H. Martin of Green Grove, An effort was made to influence this organism Miss. (see vol. iii, No. 12, this journal), who by large doses of methyl-blue, but this was says: “ A patient with malarial hematuria has unsuccessful, and patient was finally cured by a malaria to fear least of all.”—Memphis Journal total of eighty grains of quinine.

Medical Sciences. The sixth subject of this paper was a typical malarial hemoglobinuria. He was a sergeant The New York World pays the following in the East African Colonies, and had to be

compliment to the medical profession: relieved from duty on account of physical

A recent case has brought to public attention derangements, due to the prolonged malarial

the attitude of the medical profession towards intoxication. On his return he looked well, no

doctors who keep secret discoveries made by changes in organs, red corpuscles 5.75 million,

themselves, or secure patents on such, or otherwhite, 12,000; no plasmodia. Ten days later

wise seek to make their discoveries a source of paroxysms, with extremely high fever, delirium, exclusive profit to themselves. The doctors etc., resulting in grave physical and psychical

call this quackery and refuse to have relations depressions. Author saw patieut twenty-five days with the men who practice it, and for this many later, looking very pale, weak, without fever ;

persons regard the profession as narrow-minded. no plasmodia. On following day suddenly vio

But the doctors are right. It is not in their lent paroxysms, very marked icterus, spleen own but in humanity's interest that they hold and liver greatly swollen, urine deep brown-red, each other to this rule of ethics. It is the containing enormous quantities of hemoglobin, doctrine of the profession-as old as Galenno red blood disks. No plasmodia in blood.

that the first duty of the doctor is to humanity, Two days later there were 1.75 million red that his learning and his skill belong to mancorpuscles to c. c., a diminution of four million kind, not to himself. Hence it is held to be in six days, their form pormal, and very numer. his obligation to give to the profession, for huous examinations of fresh and stained specimens manity's benefit, whatever discovery or device on this and succeeding days failed to reveal any he may niake tending to the saving of life or parasite whatever. On the seventh day the the mitigation of suffering. To this, moreover, red disks reached their minimum, one million ;

every physician upon graduation makes oath of on the ninth the white ones had sunk to 2,800. allegiance, so that the doctor who violates the Changes then took place with great rapidity, ethical rule disregards his own oath and is not megalocytes? of a very pale color, then giganto a person to be trusted. Even his pretensions blasts, the numerous mycrocytes, 3 poikilo as to his discovery must be taken as that of a cytes ; - in short, all the characteristic elements

man unworthy of confidence. This rule is a of the so-called pernicious anemia made their

generous, not a narrow-minded one. It has its appearance in rapid order. Then, with the source in a high and unselfish conception of cessation of sever,5 a rapid regeneration, all the duty, and its rigid enforcement is a matter of morphologically altered, red disks disappeared, true morality as well as of professional ethics. preceded by an enormous increase of white - Medical Standard.

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from their center which again become free, attack new corpus cles, and precipitate a fresh paroxysm. The first form, found by Marchiafava and Celli in summer and fall malarias, exhibit a mainly, though not purely, quotidian type, require twenty four hours for completion of cycle, the sporulative forms being rarely found in circulating blood, but always in internal organs. This form generally causes the quotidian type of the Italian summer and fall malarias.

The second, discovered by Golgi, requires twice twenty-four hours for completion of cycle, the third, also described by Golgi, requiring three times twenty-four hours.

If two generations of the tertian type are found, of wbich each matures twenty-four hours apart, we have a pure quotidian ague, or rather a bitertiana duplex, whilst in case of the quartan three generations may alternate and give rise to daily chills, really a triquartana triplex.

1' Very large, pale, red blood corpuscles.
2 Nucleated red blood corpuscles.
3 Very small red corpuscles,
4 Very irregularly shaped red corpuscles.

Fifteen grains quinine had been given experimentally at first, although there were no plasmodia. It failed, and was replaced by very concentrated food, stimulants, later arsenic.

TAE CREATOR Knows “ Doctor," said the patient, “ I believe there's is something wrong with my stomach.'

"Not a bit of it,” replied the doctor promptly. “ God made your stomach and He knows how to make them. There's is something wrong with the stuff you put in it, may be, and something wrong in the way you stuff it in and stamp it down, but your stomach is

CHRONIC URETHRITIS is treated by Dr. A. G. of the brawny protuberant portion, inserted Gerster, of New York, by injections of a 1-2000 a crystal of pure carbolic acid into each solution of potassium permanganate, carried to cavity that was so formed; the crater was a point between the sphincter of the bladder thoroughly cleansed of pus and slough, and and the cut-off muscle..

freely dusted with a mixture of equal parts of A marked improvement, usually, quickly fol. oxide of zinc and iodoform, and the whole was lows, and on the degree of improvement de covered over with carbolized lint. pends the frequency with which the applica. The next morning the patient was almost free tions should be made.

from pain, and hence much more cheerful. I In very chronic cases it is necessary to resort removed several sloughs, scraped the softened to the deep injection of from three to five min portions of the mass, dusterl in iodoform and zinc ims of a five per cent. solution of nitrate of over the cavity and inserted six or seven crystals silver, once, twice or three times a week, accord- of carbolic acid in various directions. Acid and ing to the severity of the case.

bark was ordered to be taken three times daily, These injections are made after the patient and the urine was examined and found to be has urinated.

free from sugar. He is placed on his back and the injector in This treatment was continued daily for a week, troduced beyond the cut-off muscle into the at the end of which time all the surrounding neck of the bladder, but not into the bladder. brawny tissues had broken down, and most of

It is at this point that the trouble lies, between the sloughs had separated, leaving a large, cut-off muscle and the vesical sphincter.—Medic healthy granulating cavity which was dusted cal Mirror,

as before, and the patient was soon well enough

to leave his bed and go about. An Enormous Carbuncle; Crystals of Car- SURGN.-CAPT. E. HAROLD Brown, I M.S. bolic Acid Applied; Recovery.

Civil Surgeon, Cooch-Behar. On the 28th of last June I was asked to

. - Indian Med. Record. see a Mahommedan named Sher Jan Khan, aged 43 years, who was suffering from car Treatment of Asthma by Pilocarpine. buncle. The patient had been ill for more A middle-aged woman (wife of a pensioned than a month, having been treated at first soldier) was subject to asthma for some years, by a kobiraj and afterwards, up to the time and was treate i by several medical men by I was called in, by a regular practitioner, various methods, which gave her only temwho had just left the town. I was told that it porary relief. When she placed herself under was a serious case, but was not prepared for the my treatment I also had primarily tried many sight which met my eyes when the patient's methods, such as drug-smoking, medicated steam back was uncovered; there was a large, deep inhalations, etc., without any effect. cavity between and below the shoulder-blades, In this perplexity I took advantage of a few as wide across the top of a full-sized breakfast hints from the Indian Medical Record, and havcup, and two inches in depth. Its floor was ing preferred pilocarpine tried it in one-sixthcovered with pus and shreds of slough, on re grain doses at bed-time for three days, and the moving which some of the muscles of the back patient having felt relieved to a great extent I were exposed. Surrounding this huge cavity continued the same thrice daily for a week, and was a protuberant mass rising an inch above the patient was quite relieved, and for the past the general surface; it was a reddish-blue four months she has had no return of the com. color, hard and riddled with small orifices, each plaint. containing a slough. From side to side of this It is, however, left to be seen whether the mass across the central crater was a measure cure, so promising, will prove radical and perment of ten inches, and from above downwards manent, or only palliative. eight and a half inches-truly an enormous car. In conclusion, it is suggested that this remedy buncle.

having proved so efficacious in the case cited The patient was very weak and low, worn above, which resisted so many varieties of treatout by the continuous pain and profuse dis ment, be given a fair trial in other cases and charge He had lost considerable flesh, was results reported in the Record. In another case, unable to leave his bed, and was altogether in it may be mentioned, that I have tried tincture such a low state that I gave a very guarded of jaborandi in ten-minim doses every three prognosis.

hours, and the patient was relieved of the more The treatment which had been adopted up to prominent symptoms; but I am not aware this time was poulticing the part three or four whether the patient was permanently cured, as times daily and dressing it with carbolic oil. he refrained from further treatment. I immediately interdicted poulticing, and

By B. V. KASAVIAH. extracted several sloughs from various parts Hospital Assistant, Aurangabad.Ibid.

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Sometimes it will be found necessary to use In cases of leucorrhea or vulvitis, occurring other tampons in place of those wet with alcoin young girls in which there is no true vagi hol and carbolic acid, particularly if a detergent pitis or metritis, the local treatment and the influence is required, such as follows: inflammation about the vulva is to be combated. R. Tannic acid...... This treatment is both local and general.

Pure glycerin ...........

................. 3iij

The parts are to be washed carefully with astringent

It is worthy of notice that in vaginal injecdecoctions cr with a weak solution of Goulard's

tions in cases of leucorrhea it is necessary to extract. After this has been done, the washing

employ large quantities of liquid.— Therap.

Gazette. may be carried out by weak solutions of bichloride of mercury and by baths and lotions.

Class-Room Notes. In other cases, carbolic acid, in the strength of 5 parts to 1,000 of water, may be employed;

From the College and Clinical Record.

PROF. HARE gave the class the following for and, finally, in obstinate cases, a solution of

mula for A Good Liniment : nitrate of silver, in the strength of 3 grains to

R. Tinc. aconiti.. the ounce, may be resorted to. In the intervals

Tinct. opii....

Lin.saponis... between the bathings, the parts are to be sepa M. rated by lint impregnated with a weak solution For a case of Subacute Bronchitis in a young of carbolic acid, or covered with red precipitate man 18 years of age, Prof. Wilson prescribed ointment. The internal medication consists in the following treatment: the use of cod-liver oil with quinine, or, in R. Ammonii chloridi.......... x scrofulous children, the use of arsenical prepara

M. Every three hours. And tions. In place of these lotions, leucorrhea may R. Strychninæ sulphat..

... gr. 1-18 be treated by powders, such as the following:

In pill three times a day.

Also at night give ipecac as an emetic to get R. Powdered starch....

........Jij Subnitrate of bismuth......

rid of the mucous expectoration and thus give Sig.--Mix very thoroughly, and dust the vagina with this him a good night's rest. powder.

In cases where good results do not follow the FOR Urticaria Prof. Henry W. Stelwagon use of starch, powdered acetate of lead or tannin recommended as a local application the followmay be used, provided care is taken that they

• Acid, carbolic...

............... 3ij are pure. Frequently this treatment is useful

Acid boric..

........... 3iv after the injections above named have been em


..f zij ployed. With this treatment the following pre

Aquæ... .............. ................... pint j

M. scription is given internally:

The systemic treatment should be the reR. Powdered sulphate of iron....................... Subcarbonate of iron.....

moval of ihe cause. Any disturbance of Powdered red cinchona bark.......

digestion must be corrected, if possible, and Pulverized cinnamon.. Ergotine...........

the diet should be of a simple character. A small pinch of this powder may be given DR. ORVILLE HORWITZ (Demonstrator of with the principal meals, and is particularly Surgery) recommended the following local treatuseful at the approach of the menstrual epochs. ment for Spermatorrhea. On the first day Prolonged injections, morning and night, of give a deep urethral injection of 1 per cent. of cold water, to which has been added a little carbolic acid; on the second day at per cent. vinegar, may also be advisable.

solution; on the third day a 1 per cent. solution In cases of gonorrheal vaginitis the discharge and on the fourth day a 1 per cent. solution of may be stopped by the following:

sulphate of zinc, and increase the strength of R. Tannic acid..

the solution daily until it is a 7 per cent.

solution. Usually the treatment may then be M. Sig.-Make a solution, and by the aid of the speculum introduce two tanypons saturated with this solution.

discontinued. If needed, a third tampon may be inserted. In the case of a young man aged 19 years, After twenty-four hours these tampons may who had been subject to attacks of Persisbe removed and cleansing injections used, tent Hiccough for the past three years (the after which other tampons may be employed. attacks lasting two or three weeks) and who Rest in bed is to be strepuvusly advised.

had been treated by the use of bromide of In other cases a solution made up as follows sodium and chloral, neither of the drugs havwill be equally advantageous :

ing any effect, Prof. Wilson prescribed the R. Carbolic acid. ....................grains xv

inhalation of nitrite of amyl two or three times Alcohol or cologne........................................... 3i


a day. Sig.-Mix, and by the aid of the speculum once or twice a day for a case of Hysterical Attacks of Pain in insert tampons, wet in this solution and practice astringent injeo

the hypogastric region, in a young man aged

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Water ...................




R. Zinci valerianat.


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Potassii chlorat........


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29 years, Prof. Da Costa prescribes the follow. be used are arsenic, which is excellent; nitroing treatment:

glycerine (1-200, 1-100 gr. three times a day)

and the nitrates ; preparations of iodine (iodide . Extract M.

of sodium) in cases of lung complications. In pill three times a day. Also every night a Blisters are of no use. It is very important pill of aloin, grain 1-5, aromatic powder q.s.; that the patient's urinary secretions should be and if this is not sufficient to keep his bowels looked after. open daily, he should take one in the morning

PROF. HARE said that sugar of milk is a dealso. He must also moderate the use of

use of cided diuretic; that in Dropsy (either renal or tobacco.

cardiac) sugar of milk, ounces j in a pint of PROF. BRINTON said that in the treatment of water, taken during the day, will cause profuse Tetanus we should try to get rid of the exciting diuresis. cause by disinfecting the wound and by anti

PROF. Henry W. STELWAGON gave the fol. septic dressings. Keep the patient out of drafts

lowing prescription for an ointment for a case of air, as in his experience they will cause the

of Scabies : paroxysms. For the spasms, ether may be

R. Sulphur præcipitat .....

......... Sij given and ice may be applied to the spine,

Beta naphthol... but be careful on account of the depressing

Balsam Peruvian.

Adipis, ad........... effect of the cold. He relies more on chloral

FUR Acute Aginose Sore Throat Prof. Hare and bromide of potassium. Calabar bean has been recommended, but he has never seen any

recommended the use of a gargle, the formula good results from its administration. The

of which is as follows:

R. Extract rhus glabræ fuid......................... f3ss patient should be supported by nourishing food, either by the mouth or by enemata, as the longer the patient is kept alive the greater the chance there is of his recovery.

For a case of Hystero-epilepsy in a man aged .

45 years, Prof. Wilson prescribed sulfonal, For a mild case of Erythematous Eczema, in five-grain doses, three times a day, and Prof. Henry W. Stelwagon prescribed a lotion directed that the patient's secretions be kept of carbolic acid, drama ij, to water fluid-ounces j. active. He must not become constipated, and

PROF. Hare said that grindelia robusta is one should be as much as possible in the open air. of the best remedies for the treatment of the In order to prevent the unpleasant head Poison of Rhus Toxicodendron, or poison ivy. symptoms that usually follow the administra

The treatment of Asthma, Prof. Da Costa tion of large doses of quinine and salicylic acid, divided into three heads. First, that for the

hat for the Prof. Hare said that large doses of the broparoxysm: Give a plentiful supply of fresh,

mides may be given at the same time and usupure air and some remedy to relieve the spasm ally will be entec -ether (internally, twenty drops) or chloro. For the treatment of Erythema Intertrigo, form or chloral, also, dry cupping the chest Prof. Henry W. Stelwagon recommended the and some slightly nauseating agent which will following lotion as a very good one: promote expectoration. Apomorphia is very R. Pulv. calaminæ.

Pulv, zinci oxid.......

..đi Bị useful; so are the salts of ammonium. Other remedies that may be used for the spasm are to

Alcoholis... burn paper that has been saturated with nitrate M. of potassium (nitre paper), inhalation of steam, If the case is an obstinate one, attention and strong, hot coffee.

should be paid to the general health. Secondly, remedies to prevent the paroxysm : Smoke stramoniuin. This is undoubtedly ef Prof. Hare said that pilocarpine is of most fective, and may be smoked in an ordinary good in renal dropsy and is of the least good in pipe or thrown on a hot coal and inhaled. cardiac dropsy. For Acute Suppression of Belladonna is useful; as is also the combina. Urine he recommended the administration of tion of belladonna, camphor and stramonium minute doses of pilocarpiue (1.30 to 1.60 of a in the form of cigarettes. Nitrite of amyl may grain'. prevent it, but cannot be depended on.

Prof. HARE said that chlorate of potassium, Thirdly, the treatment to get rid of the disease: used as a mouth-wash, is the very best remedy Change of air; each case 18 a law to itself. that can be used for Sto natitis. and recomColorado and New Mexico are the best climates. mended the following preparation : The food should be plain and no heavy suppers.

R. Potassii chlorat....................... XXX The bowels should be kept open and the patient

Tincture myrrhæ..... should be dressed warmly. Remedies that may M. Use as a mouth-wash.



Elixir calisa yæ, 9. S.................



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