Kava: From Ethnology to PharmacologyKava is an herb that has been used for ceremonial, ritual, religious, social, political, and medicinal purposes for centuries. In the past few decades, kava has been widely marketed as an over-the-counter treatment for anxiety, stress, restlessness, and sleep disorders. Kava: From Ethnology to Pharmacology describes the history, botanical origins, production, economic aspects, and chemical and biological properties of this medicinal herb. A major part of the book focuses on the chemical and pharmacological properties of kavalactones, the psychoactive constituents of kava that reportedly have sedative, anxiolytic, analgesic, local anesthetic, anticonvulsant, and neuroprotective properties. Clinical and medical studies that provide evidence of kava's therapeutic benefits are balanced with an assessment of the known adverse effects and interactions in which kava has been implicated. With contributions from experts in the field, this volume presents a comprehensive view of the traditional aspects of kava and the latest applications for the herb. It is a valuable reference for botanists, phytochemists, toxicologists, physicians, pharmacists, herbalists, and alternative medicine practitioners. |
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Achenbach activity adverse alcohol areas benzodiazepines beverage Borsche Cabalion chemical Chemische Berichte chemotypes chromatography clinical compounds concentrations crop cultivars cultivated desmethoxyyangonin dihydrokavain dihydromethysticin disease dose double blind drink kava drinkers drug Duffield Duve effects of kava etal Figure Fiji Fijian Futuna GABAA receptor HAMA Hänsel etal harvested Hawai’i IC50 values increase inhibition internodes isolated Journal kava circles kava consumption kava drinking kava extract kava plants kava preparation kava production kava resin kava root kava’s kavain kavalactone content kavalactones Klohs etal lactones Lebot and Lévesque Lebot etal Melanesia metabolites methystic acid methysticum plant Meyer mice muscle Na+]i oral oxazepam Pacific islands Papua New Guinea patients pharmacological Piper methysticum Piper methysticum Forst placebo placebo group placebo-controlled platelets Pohnpei Polynesian produced psychoactive reduced reported rootstock Samoa significant Singh South Pacific species stems structure symptoms Tahiti Tonga traditional Vanuatu Wallis and Futuna wichmannii Yadhu yangonin yaqona
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Page 135 - Acute effects of kava, alone or in combination with alcohol, on subjective measures of impairment and intoxication and on cognitive performance. Drug Alcohol Rev.
Page 135 - Duffield PH, Jamieson DD, Duffield AM. Effect of aqueous and lipid-soluble extracts of kava on the conditioned avoidance response in rats.