Response Variability to Psychotropic DrugsW. Janke |
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Page 74
... alcohol dehydrogenase ( Edwards and Evans , 1967 ) the latter of which is distributed to about 5- 20 % in Caucasians ... alcohol dehydrogenase differ in pH - optimum ( the a- typical enzyme showing a several fold higher in vitro activity ...
... alcohol dehydrogenase ( Edwards and Evans , 1967 ) the latter of which is distributed to about 5- 20 % in Caucasians ... alcohol dehydrogenase differ in pH - optimum ( the a- typical enzyme showing a several fold higher in vitro activity ...
Page 79
... alcohol . Although Kelly and coworkers ( 1958 ) themselves cast doubt on their results with respect to sex differences obtained with 800 mg mepro- bamate their results may be taken as pointing to the same effect : Males were improved in ...
... alcohol . Although Kelly and coworkers ( 1958 ) themselves cast doubt on their results with respect to sex differences obtained with 800 mg mepro- bamate their results may be taken as pointing to the same effect : Males were improved in ...
Page 267
... alcohol . He designs an experiment with two levels of dosages of drug and alcohol . By injecting the drugs in animals he can be sure that at every level of drug every dosage of alcohol is the same . Or : if the observable in this ...
... alcohol . He designs an experiment with two levels of dosages of drug and alcohol . By injecting the drugs in animals he can be sure that at every level of drug every dosage of alcohol is the same . Or : if the observable in this ...
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn