Response Variability to Psychotropic DrugsW. Janke |
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Page 63
... Debus ( 1968 ) . Experimental studies on antianxiety agents with normal subjects : Methodological considerations and re- view of the main effects . In O. Efron , J. Cole , J. R. Lewine , and J. R. Wittenborn ( Eds ...
... Debus ( 1968 ) . Experimental studies on antianxiety agents with normal subjects : Methodological considerations and re- view of the main effects . In O. Efron , J. Cole , J. R. Lewine , and J. R. Wittenborn ( Eds ...
Page 137
... Debus and Janke ( 1978 ) which arise in comparing different drugs thrown together into identical pharmacological categories . INTERACTION EFFECTS AND THE YERKES - DODSON LAW So far we have dealt exclusively with main effects , i.e. with ...
... Debus and Janke ( 1978 ) which arise in comparing different drugs thrown together into identical pharmacological categories . INTERACTION EFFECTS AND THE YERKES - DODSON LAW So far we have dealt exclusively with main effects , i.e. with ...
Page 218
... Debus and Longo , 1979 ) . There are almost no studies investigating individual differences in the response to antidepressant drugs . Two questions arise when studying individual ... Debus and K. J. Ehrhardt G Debus and K J Ehrhardt.
... Debus and Longo , 1979 ) . There are almost no studies investigating individual differences in the response to antidepressant drugs . Two questions arise when studying individual ... Debus and K. J. Ehrhardt G Debus and K J Ehrhardt.
Contents
Drug Response Variability Overview of Contributing Factors | 31 |
Somatic factors as predictors of psychotropic drug response | 67 |
Genetic and early environmental factors in response variability | 97 |
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activity administration adrenergic drugs alcohol amitriptyline analysis antidepressant anxiety arousal behavioral biochemical blood levels changes chlordiazepoxide chlorpromazine Claridge Clin clinical concentration correlation Debus depressant drugs depressed patients diazepam DiMascio dose drug effects drug metabolism drug postulate drug response variability drug tolerance emotional responses environmental and situational enzyme evidence experiment experimental extraverts females genetic factors H. J. Eysenck hexobarbitone imipramine increase individual differences influence interaction introverts investigated iproniazid Janke kinetic Lienert lofepramine male measures ment meprobamate neurotic neuroticism nicotine nortriptyline orciprenaline performance personality traits pharmacokinetic Pharmacol pharmacological physiological placebo plasma levels prediction predictors pretreatment Psychiatry psychoactive drugs Psychol psychological psychopharmacology psychotropic drugs questionnaire reactions relationship reported response variability sample sedation threshold significant situational conditions smoking behaviour somatic specific stimulant studies subjects scoring symptoms Table theory therapeutic tion tranquilizers treatment variability to psychotropic variance Wesnes Wittenborn